New hope for rare hunger disorder: drug shows promise in Long-Term trial

NCT ID NCT07197034

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests whether ARD-101 can safely reduce extreme hunger and food-related behaviors in people with Prader-Willi syndrome over 12 months. About 90 participants who completed a prior study will take the drug daily and visit the clinic regularly. The goal is to improve quality of life by controlling the constant urge to eat.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hyperphagia Prader-Willi syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, 16499, South Korea

  • Alberta Children's Hospital Research Institute

    Calgary, Alberta, T3B 6A8, Canada

  • Ann and Robert H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611-2991, United States

  • Centre Hospitalier Universitaire Sainte-Justine

    Montreal, Quebec, H3T 1C5, Canada

  • Children's Hospital Colorado

    Denver, Colorado, 80045-7106, United States

  • Children's Hospital at London Health Sciences Centre

    London, Ontario, N6A 5W9, Canada

  • Children's Hospital of Orange Country

    Orange, California, 92868, United States

  • Children's of Alabama

    Birmingham, Alabama, 35233-1711, United States

  • Cook Children's Medical Center

    Fort Worth, Texas, 76104, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30322-1047, United States

  • Fulborn Hospital

    Cambridge, CB21 5EF, United Kingdom

  • Inha University Hospital

    Incheon, 22332, South Korea

  • Leicester Royal Infirmary

    Leicester, LE1 5WW, United Kingdom

  • Maimonides Medical Center

    Brooklyn, New York, 11219-2918, United States

  • NYU Langone Children's Ambulatory Care Center

    Mineola, New York, 11501-4077, United States

  • Nemours Children's Clinic Wilmington

    Wilmington, Delaware, 19803-3607, United States

  • Queensland Children's Hospital

    South Brisbane, Queensland, 4101, Australia

  • Rady Children's Hospital

    San Diego, California, 92123, United States

  • Royal Hospital for Children (Glasgow) - PPDS - PIN

    Glasgow, G51 4TF, United Kingdom

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050, Australia

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • Stanford Children's Health Specialty Services

    Palo Alto, California, 94304, United States

  • Stollery Children's Hospital

    Edmonton, Alberta, Canada

  • The Children's Hospital at Westmead

    Westmead, New South Wales, 2145, Australia

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21287-0005, United States

  • The Royal London Hospital

    London, E1 1BB, United Kingdom

  • UF Shands Children's Hospital

    Gainesville, Florida, 32610-3008, United States

  • University of Minnesota Masonic Children's Hospital

    Minneapolis, Minnesota, 55102, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232-0005, United States