New drug trial aims to tame uncontrollable hunger in rare genetic disorder

NCT ID NCT06828861

Summary

This study is testing whether an investigational drug called ARD-101 can reduce the extreme, life-threatening hunger (hyperphagia) experienced by people with Prader-Willi syndrome. About 90 participants, aged 7 and older, will take either ARD-101 or a placebo pill daily for 12 weeks. Researchers will compare the two groups to see if the drug safely helps control food-seeking behaviors and improves quality of life for patients and their caregivers.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, 16499, South Korea

  • Alberta Children's Hospital Research Institute

    Calgary, Alberta, T3B 6A8, Canada

  • Ann and Robert H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611-2991, United States

  • Centre Hospitalier Universitaire Sainte-Justine

    Montreal, Quebec, H3T 1C5, Canada

  • Children's Hospital Colorado

    Denver, Colorado, 80045-7106, United States

  • Children's Hospital at London Health Sciences Centre

    London, Ontario, N6A 5W9, Canada

  • Children's Hospital of Orange Country

    Orange, California, 92868, United States

  • Children's of Alabama

    Birmingham, Alabama, 35233-1711, United States

  • Cook Children's Medical Center

    Fort Worth, Texas, 76104, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30322-1047, United States

  • Fulborn Hospital

    Cambridge, CB21 5EF, United Kingdom

  • Inha University Hospital

    Incheon, 22332, South Korea

  • Leicester Royal Infirmary

    Leicester, Leicestershire, LE1 5WW, United Kingdom

  • Maimonides Medical Center

    Brooklyn, New York, 11219-2918, United States

  • NYU Langone Children's Ambulatory Care Center

    Mineola, New York, 11501-4077, United States

  • Nemours Children Clinic Wilmington

    Wilmington, Delaware, 19803-3607, United States

  • Queensland Children's Hospital

    South Brisbane, Queensland, 4101, Australia

  • Rady Children's Hospital

    Encinitas, California, 92123, United States

  • Royal Hospital for Children (Glasgow) - PPDS - PIN

    Glasgow, G51 4TF, United Kingdom

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050, Australia

  • Samsung Medical Center

    Seoul, South Korea, 06351, South Korea

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • Stanford Children's Health Specialty Services

    Palo Alto, California, 94304, United States

  • Stollery Children's Hospital

    Edmonton, Alberta, T6G 2B7, Canada

  • The Children's Hospital at Westmead

    Westmead, New South Wales, 2145, Australia

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21287-0005, United States

  • The Royal London Hospital

    London, E1 4NS, United Kingdom

  • UF Shands Children's Hospital

    Gainesville, Florida, 32610-3008, United States

  • University of Minnesota Masonic Children's Hospital

    Minneapolis, Minnesota, 55102, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232-0005, United States

Conditions

Explore the condition pages connected to this study.