New hope for tough gout cases: experimental combo targets stubborn uric acid

NCT ID NCT07116746

First seen Dec 29, 2025 · Last updated May 14, 2026 · Updated 18 times

Summary

This study tests a new drug called AR882 combined with a standard gout medication (XOI) in 25 adults with uncontrolled gout who had severe reactions or failed uricase therapy. The goal is to lower uric acid levels below 6 mg/dL and shrink painful uric acid crystal deposits (tophi) over 6 months. Participants must have at least one visible tophus and be at least 3 months past their last uricase infusion.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arthrosi Investigative Site (102)

    RECRUITING

    Miami, Florida, 33155, United States

  • Arthrosi Investigative Site (103)

    RECRUITING

    Duncansville, Pennsylvania, 16635, United States

  • Arthrosi Investigative Site (104)

    RECRUITING

    West Lake Hills, Texas, 78746, United States

  • Arthrosi Investigative Site (105)

    RECRUITING

    Margate, Florida, 33063, United States

  • Arthrosi Investigative Site (106)

    RECRUITING

    Jackson, Mississippi, 39202, United States

  • Arthrosi Investigative Site (107)

    RECRUITING

    Bellevue, Washington, 98004, United States

  • Arthrosi Investigative Site (108)

    RECRUITING

    Charlotte, North Carolina, 28202, United States

  • Arthrosi Investigative Site (109)

    RECRUITING

    Tampa, Florida, 33609, United States

Conditions

Explore the condition pages connected to this study.