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Can pool exercise calm overactive pain signals in arthritic knees?

NCT ID NCT07883824

Symptom relief Sponsor: Kirsehir Ahi Evran Universitesi Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 20, 2026 · Last updated Oct 21, 2026 · Updated 1 time

Summary

Researchers are studying whether exercise in a pool can reduce central sensitization, a state where the nervous system becomes extra sensitive to pain, in adults with knee osteoarthritis. The trial enrolls 60 people aged 40 to 65 who have knee osteoarthritis and no cognitive impairments. Participants are randomly assigned to either standard physical therapy exercises or a tailored hydrotherapy program. The team measures central sensitization with a questionnaire and tracks pain intensity and functional parameters to see how the two approaches compare.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aquatic exercise (pool therapy)
What this could lead to
If it works, pool-based exercise could offer a low-impact way to ease pain and improve movement for people with knee osteoarthritis.
What could go wrong
This is a small, single-center study, so any benefits may not hold up in larger groups. Pool therapy also requires access to a pool and may not suit everyone with knee arthritis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults aged 40-65 2. Individuals diagnosed with knee osteoarthritis 3. Individuals with no cognitive impairments 4. Volunteers for the study Exclusion Criteria: 1. Individuals who have undergone knee surgery 2. Individuals presenting with signs such as fracture, malignancy, or infection 3. Pregnancy 4. Individuals with cognitive impairments who are unable to express themselves.

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Conditions

The condition(s) this trial relates to.

Depression osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aquatic Central sensitization Knee osteoarthristis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Kirsehir Ahi Evran University, Kırşehir, Merkez 40100

    RECRUITING

    Kırşehir, Merkez, 40000, Turkey (Türkiye)

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