Hope for kids with painful mouth sores: new drug trial launches

NCT ID NCT04528082

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 25 times

Summary

This study tests whether the drug apremilast can reduce painful mouth ulcers in children aged 2 to 17 with Behçet's disease. About 60 participants will receive either apremilast or a placebo for 12 weeks to see if it helps heal sores and ease pain. The goal is to find a safer, effective treatment for kids with this rare inflammatory condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Agia Sofia Children Hospital

    RECRUITING

    Athens, 11527, Greece

  • Alder Hey Childrens Hospital

    RECRUITING

    Liverpool, L12 2AP, United Kingdom

  • Attikon University General Hospital

    RECRUITING

    Athens, 12462, Greece

  • Azienda Socio Sanitaria Territoriale Centro Specialistico Ortopedico Traumatologico Gaetano Pini

    RECRUITING

    Milan, 20122, Italy

  • Birmingham Childrens Hospital

    TERMINATED

    Birmingham, B4 6NH, United Kingdom

  • Centre Hospitalier Universitaire Vaudois

    TERMINATED

    Lausanne, 1011, Switzerland

  • Dokuz Eylul Universitesi Tip Fakultesi Hastanesi

    TERMINATED

    Izmir, 35330, Turkey (Türkiye)

  • Erciyes Universitesi Tip Fakultesi Hastanesi

    RECRUITING

    Kayseri, 38030, Turkey (Türkiye)

  • General Hospital of Thessaloniki Ippokrateio

    RECRUITING

    Thessaloniki, 54642, Greece

  • Hacettepe Universitesi Tip Fakultesi Hastanesi

    RECRUITING

    Ankara, 06100, Turkey (Türkiye)

  • Hopital Necker Enfants Malades

    TERMINATED

    Paris, 75015, France

  • Hopital Robert Debre

    RECRUITING

    Paris, 75019, France

  • Hospices Civils de Lyon Hopital Femme Mere Enfant

    RECRUITING

    Bron, 69677, France

  • Hospital Sant Joan de Deu

    RECRUITING

    Esplugues de Llobregat, Catalonia, 08950, Spain

  • Hospital Universitari Vall d Hebron

    RECRUITING

    Barcelona, Catalonia, 08035, Spain

  • Hospital Universitari i Politecnic La Fe

    RECRUITING

    Valencia, Valencia, 46026, Spain

  • Hospital Universitario La Paz

    TERMINATED

    Madrid, 28046, Spain

  • Hospital Universitario Ramon y Cajal

    RECRUITING

    Madrid, 28034, Spain

  • Hospital Universitario Virgen del Rocio

    RECRUITING

    Seville, Andalusia, 41013, Spain

  • IRCCS Istituto Giannina Gaslini

    RECRUITING

    Genova, 16147, Italy

  • IRCCS Ospedale Pediatrico Bambino Gesu

    RECRUITING

    Roma, 00165, Italy

  • Istanbul Universitesi Cerrahpasa Tip Fakultesi

    RECRUITING

    Istanbul, 34098, Turkey (Türkiye)

  • Istanbul Universitesi Istanbul Tip Fakultesi Hastanesi

    RECRUITING

    Istanbul, 34093, Turkey (Türkiye)

  • John Radcliffe Hospital

    RECRUITING

    Oxford, OX3 7LD, United Kingdom

  • Meir Medical Center

    RECRUITING

    Kfar Saba, 4428164, Israel

  • Ospedale Santissima Annunziata

    RECRUITING

    Chieti, 66100, Italy

  • Umraniye Egitim ve Arastirma Hastanesi

    RECRUITING

    Istanbul, 34764, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.