New vaccine aims to snuff out the common cold

NCT ID NCT07399132

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new vaccine called APL-10456 that targets rhinovirus, the main cause of the common cold. About 144 healthy adults, both younger (18-54) and older (55+), will receive either the vaccine or a placebo. The main goal is to check if the vaccine is safe and triggers an immune response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

APL-10456-Vaccine

What this could lead to

If successful, this could lead to a vaccine that prevents common colds caused by rhinovirus.

What could go wrong

This is a very early Phase 1 trial with only 144 healthy volunteers. The vaccine may not produce a strong immune response or could have unexpected side effects. Success in early phases does not guarantee a usable vaccine.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emeritus Research

    Melbourne, Victoria, 3124, Australia

  • Veritus Research

    Melbourne, Victoria, 3153, Australia