New vaccine aims to snuff out the common cold

NCT ID NCT07399132

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new vaccine called APL-10456 that targets rhinovirus, the main cause of the common cold. About 144 healthy adults, both younger (18-54) and older (55+), will receive either the vaccine or a placebo. The main goal is to check if the vaccine is safe and triggers an immune response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
APL-10456-Vaccine
What this could lead to
If successful, this could lead to a vaccine that prevents common colds caused by rhinovirus.
What could go wrong
This is a very early Phase 1 trial with only 144 healthy volunteers. The vaccine may not produce a strong immune response or could have unexpected side effects. Success in early phases does not guarantee a usable vaccine.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emeritus Research

    Melbourne, Victoria, 3124, Australia

  • Veritus Research

    Melbourne, Victoria, 3153, Australia

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