New hope for babies with SMA: trial tests Muscle-Strengthening drug

NCT ID NCT07047144

Summary

This study is testing an investigational drug called apitegromab in infants under 2 years old who have spinal muscular atrophy (SMA). The main goal is to see how the drug moves through the body, how it affects a specific muscle protein, and if it can improve gross motor skills, like sitting and crawling, over 48 weeks. All participants will also be receiving standard SMA therapy during the study.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atrium Health Wake Forest Baptist

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHR Citadelle

    RECRUITING

    Liège, 4000, Belgium

  • Centro Clinico NeMO Milano - Fondazione Serena Onlus

    RECRUITING

    Milan, 20162, Italy

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital of Orange County (CHOC)

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cook Children's Medical Center

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fondazione I.R.C.C.S. - Istituto Neurologico Carlo Besta

    RECRUITING

    Milan, 20133, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Rome, 00168, Italy

  • Helen DeVos Children's Hospital at Spectrum Health

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopital Trousseau - I-Motion

    RECRUITING

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Sant Joan de Déu Barcelona

    RECRUITING

    Barcelona, 08950, Spain

  • Hospital Universitari i Politecnico La Fecnic La Fe

    RECRUITING

    Valencia, 46026, Spain

  • Le Bonheur Children's Hospital

    NOT_YET_RECRUITING

    Memphis, Tennessee, 38103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Neurology Rare Disease Center

    RECRUITING

    Flower Mound, Texas, 75028, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Phoenix Children's Hospital

    RECRUITING

    Phoenix, Arizona, 85016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford Neuroscience Health Center (SNHC)

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital (TCH)-Clinical Care Center (CCC)

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UZ Gent

    RECRUITING

    Ghent, East-Flanders, 9000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UZ Leuven - Campus Gasthuisberg

    RECRUITING

    Leuven, 3000, Belgium

  • Universitair Medisch Centrum Utrecht

    RECRUITING

    Utrecht, 3584 CX, Netherlands

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.