New drug aims to preserve muscle during weight loss in obesity trial
NCT ID NCT06445075
First seen Jan 24, 2026 · Last updated May 16, 2026 · Updated 21 times
Summary
This study tested a drug called apitegromab in 102 overweight or obese adults who were also taking a GLP-1 medication (like Ozempic or Wegovy). The goal was to see if adding apitegromab helps preserve lean muscle mass while losing weight. Participants received either the drug or a placebo for 24 weeks, and body composition was measured with X-ray scans.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AdventHealth Translational Research Institute
Orlando, Florida, 32804, United States
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Alliance for Multispecialty Research, LLC
Norman, Oklahoma, 73069, United States
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Apex Mobile Clinical Research
Bellaire, Texas, 77401, United States
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Clinical Trials of Texas, LLC dba Flourish Research
San Antonio, Texas, 78229, United States
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Great Lakes Clinical Trials, LLC d/b/a Flourish Research
Chicago, Illinois, 60640, United States
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ProSciento CRU
Chula Vista, California, 91911, United States
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Tandem Clinical Research GI, LLC
Marrero, Louisiana, 70072, United States
Conditions
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