New eczema drug shows promise in Long-Term trial

NCT ID NCT07003425

Recruiting now Disease control Sponsor: Apogee Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study is for people with moderate-to-severe eczema who have already completed a previous APG777 trial. It aims to see if APG777 is safe and works well over a longer period. Participants will receive injections of the drug every 12 or 24 weeks and be monitored for side effects and skin improvement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

APG777 (an injectable drug)

What this could lead to

If successful, this could confirm APG777 as a safe, long-term treatment option for moderate-to-severe eczema.

What could go wrong

This is an extension study, so results depend on earlier findings. Long-term safety and effectiveness are still being evaluated, and side effects may emerge.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Fountain Valley, California, 92708, United States
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Los Angeles, California, 90024, United States
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Coral Gables, Florida, 33134, United States
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Jacksonville, Florida, 32256, United States
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Margate, Florida, 33063, United States
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Douglasville, Georgia, 30135, United States
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Skokie, Illinois, 60077, United States
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Bowling Green, Kentucky, 42101, United States
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Detroit, Michigan, 48202, United States
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Troy, Michigan, 48084, United States
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New York, New York, 10023, United States
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Wilmington, North Carolina, 28403, United States
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Boardman, Ohio, 44512, United States
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Mason, Ohio, 45040, United States
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Portland, Oregon, 97223, United States
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Pittsburgh, Pennsylvania, 15213, United States
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Charleston, South Carolina, 29425, United States
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Nashville, Tennessee, 37215, United States
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Dallas, Texas, 75230, United States
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Frisco, Texas, 75235, United States
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San Antonio, Texas, 78213, United States
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Mill Creek, Washington, 98012, United States
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Calgary, Alberta, T2J 7E1, Canada
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Calgary, Alberta, T3E 0B2, Canada
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Edmonton, Alberta, T5J 3S9, Canada
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Fredericton, Brunswick, E3B 1G9, Canada
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Ajax, Ontario, L1S 7K8, Canada
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Markham, Ontario, L3P 1X3, Canada
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Mississauga, Ontario, L4Y 4C5, Canada
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Ottawa, Ontario, K1K 4L2, Canada
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Peterborough, Ontario, K9J 5K2, Canada
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Toronto, Ontario, M3B 0A7, Canada
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Toronto, Ontario, M4E 2Y9, Canada
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Toronto, Ontario, M4W 2N4, Canada
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Montreal, Quebec, H2X 2V1, Canada
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Québec, Quebec, G1V 4X7, Canada
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Prague, 100 00, Czechia
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Prague, 16000, Czechia
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Heidelberg, Baden-Wurttemberg, 69120, Germany
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Tübingen, Baden-Wurttemberg, 72076, Germany
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Augsburg, Bavaria, 86179, Germany
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München, Bavaria, 80337, Germany
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Blankenfelde-Mahlow, Brandenburg, 15831, Germany
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Bad Bentheim, Lower Saxony, 48455, Germany
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Kiel, Schleswig-Holstein, 24105, Germany
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Hamburg, 20354, Germany
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Debrecen, Hajdú-Bihar, 4032, Hungary
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Wroclaw, Lower Silesian Voivodeship, 50-450, Poland
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Wroclaw, Lower Silesian Voivodeship, 51-503, Poland
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Lublin, Lublin Voivodeship, 20-573, Poland
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Warsaw, Masovian Voivodeship, 01-595, Poland
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Warsaw, Masovian Voivodeship, 02-482, Poland
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Gdansk, Pomeranian Voivodeship, 80-546, Poland
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Katowice, Silesian Voivodeship, 40-600, Poland
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Sosnowiec, Silesian Voivodeship, 41-218, Poland
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Szczecin, West Pomeranian Voivodeship, 71-500, Poland
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Krakow, Woj. Małopolskie, 30-727, Poland
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Lodz, 90-237, Poland
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Santiago de Compostela, A Coruña, 15706, Spain
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Las Palmas de Gran Canaria, Canary Islands, 35010, Spain
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Madrid, 28006, Spain