New device aims to make clot removal safer for lung patients

NCT ID NCT07280247

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a device that removes blood clots from the lungs of people with acute pulmonary embolism and then returns the cleaned blood back to their body. The goal is to see if this approach is safe and effective at reducing blood loss and complications. About 39 adults with intermediate-risk clots will be enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
AlphaReturn Blood Management System (device that returns filtered blood to the body after clot removal)
What this could lead to
If successful, this could make clot removal safer by reducing blood loss and the need for transfusions in people with acute pulmonary embolism.
What could go wrong
This is a small early study with only 39 participants, so results may not apply to everyone. There is a risk of device-related complications like bleeding or injury to blood vessels.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor Heart Hospital Plano

    RECRUITING

    Plano, Texas, 75093, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CentraCare Heart and Vascular Center

    RECRUITING

    Saint Cloud, Minnesota, 56303, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jacobi Medical Center

    RECRUITING

    The Bronx, New York, 10461, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Kettering Health

    RECRUITING

    Kettering, Ohio, 45429, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Methodist Healthcare

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University at Buffalo

    RECRUITING

    Buffalo, New York, 14203, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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