Can adding immunotherapy boost a stomach cancer combo?
NCT ID NCT07770113
First seen Aug 18, 2026 · Last updated Aug 18, 2026
Summary
This trial is testing whether adding an immunotherapy drug called adebrelimab to a two-drug combination of apatinib and albumin-bound paclitaxel can help people with advanced stomach or gastroesophageal junction cancer. The study enrolls adults whose cancer has progressed after first-line treatment. Participants are randomly assigned to receive either the three-drug combo or the two-drug combo alone, and researchers will compare how long the cancer stays under control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A combination of adebrelimab (an immunotherapy drug), apatinib mesylate (a targeted therapy), and albumin-bound paclitaxel (a chemotherapy drug)
- What this could lead to
- If successful, this could offer a new second-line treatment option for advanced gastric cancer, potentially extending the time before the disease progresses.
- What could go wrong
- This is a small, early-phase trial, so results may not be conclusive. The combination may cause significant side effects, and not all patients may benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The First Affiliated Hospital of Henan University of Science and Technology
RECRUITINGZhengzhou, Henan, 450000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can AI-Guided home training boost recovery from gastric cancer surgery?
- Can a new drug combo shrink Hard-to-Treat tumors?
- Can an immunotherapy combo shrink stomach tumors before surgery?
- Can adding immunotherapy to chemotherapy improve gastric cancer outcomes?
- Can immunotherapy outperform chemo after stomach cancer surgery?