Can adding immunotherapy boost a stomach cancer combo?

NCT ID NCT07770113

First seen Aug 18, 2026 · Last updated Aug 18, 2026

Summary

This trial is testing whether adding an immunotherapy drug called adebrelimab to a two-drug combination of apatinib and albumin-bound paclitaxel can help people with advanced stomach or gastroesophageal junction cancer. The study enrolls adults whose cancer has progressed after first-line treatment. Participants are randomly assigned to receive either the three-drug combo or the two-drug combo alone, and researchers will compare how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
A combination of adebrelimab (an immunotherapy drug), apatinib mesylate (a targeted therapy), and albumin-bound paclitaxel (a chemotherapy drug)
What this could lead to
If successful, this could offer a new second-line treatment option for advanced gastric cancer, potentially extending the time before the disease progresses.
What could go wrong
This is a small, early-phase trial, so results may not be conclusive. The combination may cause significant side effects, and not all patients may benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GASTRIC ADENOCARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of Henan University of Science and Technology

    RECRUITING

    Zhengzhou, Henan, 450000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.