Prostate drug tested in bladder cancer: does it hit the right target?
NCT ID NCT05521698
Summary
This early-stage study is testing whether a drug called apalutamide, which is used for prostate cancer, affects a specific protein (EGFR) in bladder cancer cells. Researchers want to see if blocking male hormones influences this protein, which is linked to cancer progression. The study will involve 80 men with non-muscle invasive bladder cancer, who will take either the drug or a placebo pill for about 3 weeks before standard surgery.
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Contacts and locations
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Locations
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Cedars Sinai Medical Center
Los Angeles, California, 90048, United States
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National Cancer Institute Urologic Oncology Branch
Bethesda, Maryland, 20892, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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University of Arizona Cancer Center - Prevention Research Clinic
Tucson, Arizona, 85719, United States
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University of Rochester
Rochester, New York, 14642, United States
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University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792, United States
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Conditions
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