New hope for prostate cancer: drug slows disease in High-Risk patients

NCT ID NCT04108208

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 26 times

Summary

This study tests the drug apalutamide in Chinese men with a type of prostate cancer that has stopped responding to hormone therapy but hasn't spread. The goal is to see if it can delay a rise in PSA levels, a key sign of cancer progression. Participants will receive either apalutamide or a placebo, and researchers will monitor side effects and PSA response.

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Contacts and locations

Locations

  • Beijing Friendship Hospital

    Beijing, 100050, China

  • Beijing Hospital

    Beijing, 100730, China

  • Cancer Hospital Chinese Academy of Medical Sciences

    Beijing, 100021, China

  • Cancer Hospital, FuDan University

    Shanghai, 200032, China

  • Chongqing University Cancer Hospital

    Chongqing, 400030, China

  • First Affiliated Hospital SooChow University

    Suzhou, 215006, China

  • Fujian Medical University Union Hospital

    Fuzhou, 350001, China

  • Guangzhou First Municipal People's Hospital

    Guangzhou, 510180, China

  • Huadong Hospital Affiliated to Fudan University

    Shanghai, 200400, China

  • Huashan Hospital Fudan University

    Shanghai, 200040, China

  • Hunan Cancer hospital

    Changsha, 410013, China

  • Nanjing Drum Tower Hospital

    Nanjing, 210008, China

  • Peking University First Hospital

    Beijing, 100034, China

  • Peking University People's Hospital

    Beijing, 100044, China

  • Peking University Third Hospital

    Beijing, 100191, China

  • Renji Hospital, Shanghai Jiaotong University School of Medicine

    Shanghai, 200240, China

  • Shanghai Zhongshan Hospital

    Shanghai, 200032, China

  • Sichuan Provincial Peoples Hospital

    Chengdu, 610072, China

  • Sun Yat-Sen Memorial Hospital Sun Yat-sen University

    Guangzhou, 510120, China

  • The Fifth People's Hospital of Shanghai, Fudan University

    Shanghai, 200240, China

  • The First Affiliated Hospital Zhejiang University College of Medicine

    Hangzhou, 310003, China

  • The First Affiliated Hospital of Ningbo University

    Ningbo, 315010, China

  • The First Affiliated Hospital of Xian Jiaotong University

    Xi'an, 710061, China

  • TongJi Hospital of TongJi Medical College of Huazhong University of Science & Technology

    Wuhan, 430030, China

  • Wuxi People s Hospital

    Wuxi, 214023, China

  • Zhejiang Cancer Hospital

    Hangzhou, 310022, China

  • Zhejiang Provincial People's Hospital

    Hangzhou, 310000, China

Conditions

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