New drug combo shows promise in keeping High-Risk prostate cancer at bay

NCT ID NCT04523207

Completed Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Apr 23, 2026 · Last updated May 06, 2026 · Updated 3 times

Summary

This study tested whether adding apalutamide to standard hormone therapy after prostate removal surgery could delay cancer recurrence in 108 men with high-risk, non-spreading prostate cancer. The treatment aims to keep prostate-specific antigen (PSA) levels low, a sign that the cancer has not returned. Results showed that most men had no biochemical recurrence at 24 months, suggesting the combination may help control the disease, though long-term management is still needed.

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Contacts and locations

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Locations

Adult Pediatric Urology & Urogynecology, P.C

Omaha, Nebraska, 68114, United States
Arizona Urology Specialists

Tucson, Arizona, 85741, United States
Arizona Urology Specialists 1

Tucson, Arizona, 85704, United States
Arkansas Urology

Little Rock, Arkansas, 72211, United States
Associated Medical Professionals

Syracuse, New York, 13210, United States
Associated Urologists of North Carolina

Raleigh, North Carolina, 27612, United States
Carolina Urologic Research Center

Myrtle Beach, South Carolina, 29572, United States
First Urology, PSC

Jeffersonville, Indiana, 47130, United States
Foothills Urology - Golden Off

Lakewood, Colorado, 80228, United States
Genesis Research

Torrance, California, 90505, United States
Great Lakes Physician PC d/b/a Western New York Urology Associates

Cheektowaga, New York, 14225, United States
Houston Metro Urology

Houston, Texas, 77027, United States
Idaho Urologic Institute

Meridian, Idaho, 83642, United States
Lancaster Urology

Lancaster, Pennsylvania, 17604, United States
Lexington Urology

West Columbia, South Carolina, 20169, United States
Michigan Institute of Urology, PC

Troy, Michigan, 48084, United States
MidLantic Urology

Bala-Cynwyd, Pennsylvania, 19004, United States
New Jersey Urology LLC

Voorhees Township, New Jersey, 08043, United States
Ochsner LSU Health Shreveport - Regional Urology

Shreveport, Louisiana, 71106, United States
Oregon Urology Institute

Springfield, Oregon, 97477, United States
Skyline Urology

Sherman Oaks, California, 91411, United States
Spokane Urology

Spokane, Washington, 99202, United States
The Iowa Clinic

West Des Moines, Iowa, 50266, United States
The Urology Center of Colorado

Denver, Colorado, 80211, United States
The Urology Group

Cincinnati, Ohio, 45212, United States
Urological Research Network

Hialeah, Florida, 33016, United States
Urology Associates

Nashville, Tennessee, 37209, United States
Urology Austin

Austin, Texas, 78745, United States
Urology Of Virginia, Pllc

Virginia Beach, Virginia, 23462, United States
Urology San Antonio Research

San Antonio, Texas, 78229, United States
Virginia Urology

Richmond, Virginia, 23235, United States
Wichita Urology Group

Wichita, Kansas, 67226, United States

Conditions

Explore the condition pages connected to this study.

PROSTATIC NEOPLASMS