New drug combo tested for Tough-to-Treat cancers

NCT ID NCT06360354

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

Summary

This early-stage study is testing the safety and best dose of a new drug called anvumetostat when given with other cancer therapies. It is for adults with advanced cancers of the digestive system (like pancreatic, stomach, or bile duct cancers) that have a specific genetic change called MTAP-deletion. The main goals are to see how safe the drug combinations are and if they help control the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aichi Cancer Center
RECRUITING

Nagoya, Aichi-ken, 464-8681, Japan
Alexandra Hospital
RECRUITING

Athens, 11528, Greece
Arthur J E Child Comprehensive Cancer Centre
RECRUITING

Calgary, Alberta, T2N 5G2, Canada
Austin Health, Austin Hospital
RECRUITING

Heidelberg, Victoria, 3084, Australia
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
RECRUITING

Milan, 20162, Italy
Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States
CHU de Quebec Hopital de l Enfant Jesus
RECRUITING

Québec, Quebec, G1J 1Z4, Canada
Centre Georges Francois Leclerc
RECRUITING

Dijon, 21000, France
Centro Ricerche Cliniche Di Verona Societa responsabilita limitata
RECRUITING

Verona, 37134, Italy
Chris OBrien Lifehouse
RECRUITING

Camperdown, New South Wales, 2050, Australia
City of Hope National Medical Center
RECRUITING

Duarte, California, 91010, United States
City of Hope Orange County Lennar Foundation Cancer Center
RECRUITING

Duarte, California, 91010, United States
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
Comprehensive Blood and Cancer Center
RECRUITING

Bakersfield, California, 93309, United States
Comprehensive Cancer Centers of Nevada
TERMINATED

Las Vegas, Nevada, 89169, United States
Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Duke University
RECRUITING

Durham, North Carolina, 27710, United States
Epworth Healthcare
RECRUITING

St Albans, Victoria, 3021, Australia
European Interbalkan Medical Center
RECRUITING

Thessaloniki, 57001, Greece
Fondazione IRCCS Istituto Nazionale dei Tumori
RECRUITING

Milan, 20133, Italy
Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98106, United States
General Hospital Of Thessaloniki Papageorgiou
RECRUITING

Thessaloniki, 56429, Greece
GenesisCare -North Shore Oncology
RECRUITING

St Leonards, New South Wales, 2065, Australia
Gustave Roussy
RECRUITING

Villejuif, 94805, France
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, 150000, China
Hartford Hospital
RECRUITING

Hartford, Connecticut, 06106, United States
Herlev og Gentofte Hospital
RECRUITING

Herlev, 2730, Denmark
Hospital General Universitario Gregorio Maranon
RECRUITING

Madrid, 28009, Spain
Hospital Universitari Vall d Hebron
RECRUITING

Barcelona, Catalonia, 08035, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, Andalusia, 41013, Spain
IRCCS Istituto Clinico Humanitas
RECRUITING

Rozzano MI, 20089, Italy
Indiana University
RECRUITING

Indianapolis, Indiana, 46202, United States
Institut Bergonie
RECRUITING

Bordeaux, 33000, France
Institut Paoli Calmettes
RECRUITING

Marseille, 13009, France
Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center
RECRUITING

Yokohama, Kanagawa, 241-8515, Japan
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Mengchao Hepatobiliary Hospital of Fujian Medical University
RECRUITING

Fuzhou, Fujian, 350028, China
National Cancer Center Hospital
RECRUITING

Chuo-ku, Tokyo, 104-0045, Japan
National Cancer Center Hospital East
RECRUITING

Kashiwa-shi, Chiba, 277-8577, Japan
National Cheng Kung University Hospital
RECRUITING

Tainan, 70403, Taiwan
National Taiwan University Hospital
RECRUITING

Taipei, 10002, Taiwan
Northwest Cancer Specialists - Vancouver
COMPLETED

Vancouver, Washington, 98684, United States
Northwest Medical Specialties, PLLC
RECRUITING

Tacoma, Washington, 98405, United States
Norton Cancer Institute
RECRUITING

Louisville, Kentucky, 40202, United States
Norwalk Hospital
RECRUITING

Norwalk, Connecticut, 06856, United States
Oncology Consultants Cancer Center
TERMINATED

Houston, Texas, 77030, United States
Peter MacCallum Cancer Centre
RECRUITING

Melbourne, Victoria, 3000, Australia
Prince of Wales Hospital, Chinese University of Hong Kong
RECRUITING

Shatin, New Territories, Hong Kong
Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 1Z5, Canada
Queen Elizabeth Hospital Birmingham
RECRUITING

Birmingham, B15 2TH, United Kingdom
Queen Mary Hospital, The University of Hong Kong
RECRUITING

Hong Kong, Hong Kong
Radboud Universitair Medisch Centrum
RECRUITING

Nijmegen, 6525 GA, Netherlands
Rocky Mountain Cancer Centers
RECRUITING

Aurora, Colorado, 80012, United States
Sarah Cannon Research Institute UK
RECRUITING

London, W1G 6AD, United Kingdom
Sun Yat-Sen University Cancer Center
RECRUITING

Guangzhou, Guangdong, 510030, China
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, 450052, China
The First Bethune Hospital of Jilin University
RECRUITING

Changchun, Jilin, 130021, China
The Queen Elizabeth Hospital
RECRUITING

Woodville South, South Australia, 5011, Australia
Translational Research in Oncology US Inc, Trio Central Pharmacy
RECRUITING

Los Angeles, California, 90095, United States
US Oncology Research Investigational Products Center
RECRUITING

Irving, Texas, 75063, United States
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430022, China
United States Oncology Regulatory Affairs Corporate Office
RECRUITING

Nashville, Tennessee, 37203, United States
Universitaetsklinikum Essen
RECRUITING

Essen, 45147, Germany
Universitaetsklinikum Heidelberg
RECRUITING

Heidelberg, 69120, Germany
Universitaetsklinikum Wuerzburg
RECRUITING

Würzburg, 97078, Germany
Universitair Ziekenhuis Antwerpen
RECRUITING

Edegem, 2650, Belgium
Universitair Ziekenhuis Leuven - Campus Gasthuisberg
RECRUITING

Leuven, 3000, Belgium
Universite Catholique de Louvain Cliniques Universitaires Saint Luc
RECRUITING

Brussels, 1200, Belgium
University of California Los Angeles
RECRUITING

Santa Monica, California, 90404, United States
University of California San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States
University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States
University of Nebraska
RECRUITING

Omaha, Nebraska, 68198, United States
University of Virginia Cancer Center
RECRUITING

Charlottesville, Virginia, 22903, United States
Virginia Cancer Specialists PC
RECRUITING

Fairfax, Virginia, 22031, United States
Washington University
RECRUITING

St Louis, Missouri, 63110, United States
Yale University
RECRUITING

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED GASTROINTESTINAL, BILIARY TRACT, AND PANCREATIC CANCERS