Antibiotics after face grafts: help or hype?
NCT ID NCT01912651
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study tests whether taking antibiotics after facial reconstructive surgery with skin grafts improves healing and reduces infection. Adults with facial defects needing a full-thickness skin graft are randomly assigned to receive either a single antibiotic dose before surgery plus a week of oral antibiotics, or the single dose only. The main goal is to see if antibiotics lower the rate of graft failure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cephalexin (or clindamycin for allergic patients)
What this could lead to
If antibiotics are shown to improve graft survival, this could establish a standard practice to reduce graft failure and revision surgeries.
What could go wrong
This is a single-center Phase 4 trial; results may not apply to all patients. Antibiotics carry side effects like allergic reactions or diarrhea, and may not improve outcomes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Michigan
Ann Arbor, Michigan, 48109, United States