Antibiotics in infancy could weaken vaccine protection, study suggests

NCT ID NCT06079606

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 200 healthy infants in Iceland to see if antibiotics given early in life change how well their bodies respond to routine vaccines, including the rotavirus vaccine. Researchers will measure antibodies in saliva and blood, and also analyze stool samples to check the gut microbiome. The goal is to understand whether antibiotics might interfere with vaccine effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If this study finds a link, it could help doctors understand how antibiotics might weaken vaccine protection in infants, leading to better vaccination strategies.

What could go wrong

This is an observational study, not a treatment trial. It can show a connection but cannot prove cause and effect. Results may not apply to all populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Landspitali University Hospital

    Reykjavik, 101, Iceland