Antibiotics in infancy could weaken vaccine protection, study suggests
NCT ID NCT06079606
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 200 healthy infants in Iceland to see if antibiotics given early in life change how well their bodies respond to routine vaccines, including the rotavirus vaccine. Researchers will measure antibodies in saliva and blood, and also analyze stool samples to check the gut microbiome. The goal is to understand whether antibiotics might interfere with vaccine effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If this study finds a link, it could help doctors understand how antibiotics might weaken vaccine protection in infants, leading to better vaccination strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It can show a connection but cannot prove cause and effect. Results may not apply to all populations.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Landspitali University Hospital
Reykjavik, 101, Iceland
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