Antibiotics after bladder botox may cut infection risk

NCT ID NCT04791579

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking a short course of antibiotics (ciprofloxacin) after Botox injections into the bladder can reduce the chance of urinary tract infections. About 160 adults with neurogenic overactive bladder (due to conditions like multiple sclerosis or spinal cord injury) will be randomly assigned to receive either antibiotics or a placebo. The goal is to see if this simple step can make a common procedure safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ciprofloxacin (antibiotic)

What this could lead to

If it works, this could provide a simple way to prevent bladder infections after Botox injections, improving safety and reducing antibiotic overuse.

What could go wrong

This is a small Phase 2 trial, so results may not apply to everyone. Ciprofloxacin can cause side effects like nausea, and overuse may contribute to antibiotic resistance.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bacterial urinary tract infection Urinary Bladder, Neurogenic urinary tract infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alberta

    RECRUITING

    Edmonton, Alberta, T6G2R3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••