One shot before surgery may be enough to prevent infection
NCT ID NCT03283878
First seen Nov 20, 2025 · Last updated Apr 28, 2026 · Updated 18 times
Summary
This study looked at the best timing for antibiotics in adults having knee replacement surgery. About 1,770 people took part. The goal was to see if a single dose before surgery works as well as a full day of antibiotics to prevent joint infections.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Augusta Health
Fishersville, Virginia, 22939, United States
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BaylorScott&White Research Institute
Temple, Texas, 76508, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Duke University Medical Center
Durham, North Carolina, 27703, United States
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Emory University
Atlanta, Georgia, 30322, United States
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Mississippi Bone and Joint Clinic
Starkville, Mississippi, 39759, United States
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NYU School of Medicine
New York, New York, 10003, United States
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Ohio State University
Columbus, Ohio, 43210, United States
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Rothman Institute
Philadelphia, Pennsylvania, 19107, United States
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University Of Mississippi Medical Center
Jackson, Mississippi, 39216, United States
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University Orthopaedic Associates, LLC
Somerset, New Jersey, 08873, United States
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University of California, San Francisco
San Francisco, California, 94143, United States
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University of Maryland St. Joseph Medical Center & Orthopedic Associates
Towson, Maryland, 21204, United States
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University of South Carolina
Columbia, South Carolina, 29208, United States
Conditions
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