Could an antibiotic boost survival in severe alcoholic hepatitis?

NCT ID NCT02281929

First seen Jan 03, 2026 · Last updated May 05, 2026 · Updated 21 times

Summary

This study tested whether adding an antibiotic (amoxicillin-clavulanic acid) to standard steroid treatment could improve survival in people with severe alcoholic hepatitis. About 300 adults at high risk of death within 2 months took part. The goal was to see if the antibiotic combination helped more patients survive compared to steroids alone.

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Contacts and locations

Locations

  • CHU

    Angers, France

  • CHU

    Rouen, France

  • CHU

    Toulouse, France

  • CHU Grenoble

    Grenoble, France

  • CHU Montpellier

    Montpellier, France

  • CHU Nantes

    Nantes, France

  • CHU Nice

    Nice, France

  • CHU Poitiers

    Poitiers, France

  • CHU Pontchaillou

    Rennes, France

  • CHU d'Amiens

    Amiens, France

  • CHU de Besançon

    Besançon, France

  • CHU de Caen

    Caen, France

  • Centre Hospitalier

    Valenciennes, 59300, France

  • Centre hospitalier

    Dunkirk, France

  • Hôpital BEaujon (AP-HP)

    Clichy, France

  • Hôpital Claude Huriez, CHU

    Lille, France

  • Hôpital Jean Verdier (AH-HP)

    Bondy, 93143, France

  • Hôpital La Pitié (AP-HP)

    Paris, France

  • Hôpital Paul Brousse (AH-HP)

    Villejuif, 94000, France

  • Hôpital Saint Antoine (AP-HP)

    Paris, 75012, France

Conditions

Explore the condition pages connected to this study.