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Can antibiotics flushed into a drain fight abscesses faster?

NCT ID NCT03476941

Disease control Sponsor: University of Iowa Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This trial tests whether flushing an abdominal abscess drain with antibiotics, instead of just saline, can help clear the infection more effectively. People with an intra-abdominal abscess who have a drain in place and are receiving systemic antibiotics may join. Researchers compare the duration of systemic antibiotics needed when the drain is irrigated with gentamicin and clindamycin versus a placebo.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Gentamicin and clindamycin, antibiotics used to flush the surgical drain
What this could lead to
If it works, this approach could reduce the duration of systemic antibiotics needed after an abdominal abscess, potentially lowering side effects and speeding recovery.
What could go wrong
This is a very small, early-phase trial with only 2 participants, so results may not apply broadly. The added antibiotics could also cause irritation or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

2 people

The number who actually took part.

Started

Apr 2019

Finished

Oct 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Intra-abdominal abscess drained with catheter/drain * Treatment with systemic antibiotics * Able to consent Exclusion Criteria: * Abscess(es) not amendable for an image guided drain placement.

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Conditions

The condition(s) this trial relates to.

Abdominal Abscess

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal abscess

Contacts and locations

Locations

  • The University of Iowa

    Iowa City, Iowa, 52242, United States

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