Eye injection could stop damaging blood vessels in Herpes-Related blindness

NCT ID NCT07329686

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether injecting anti-VEGF medication directly into the cornea can safely reduce abnormal blood vessel growth caused by herpes simplex keratitis. One hundred adults will receive either the injection plus antiviral eye drops or standard antiviral drops alone. Researchers will measure changes in blood vessel area, vision, and eye clarity over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
anti-VEGF medication
What this could lead to
If successful, this could offer a new, targeted treatment to reduce abnormal blood vessels in the cornea and improve vision for people with herpes-related eye disease.
What could go wrong
This is an early Phase 1/2 trial with only 100 participants, so results are preliminary. The injection procedure itself carries risks like infection or corneal damage, and the treatment may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CORNEAL NEOVASCULARIZATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • 1 Xihu Avenue, Shangcheng District,Hangzhou, Zhejiang,China,Hangzhou, Zhejiang Completed

    RECRUITING

    Hangzhou, Zhejiang, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.