Eye injection could stop damaging blood vessels in Herpes-Related blindness

NCT ID NCT07329686

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether injecting anti-VEGF medication directly into the cornea can safely reduce abnormal blood vessel growth caused by herpes simplex keratitis. One hundred adults will receive either the injection plus antiviral eye drops or standard antiviral drops alone. Researchers will measure changes in blood vessel area, vision, and eye clarity over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

anti-VEGF medication

What this could lead to

If successful, this could offer a new, targeted treatment to reduce abnormal blood vessels in the cornea and improve vision for people with herpes-related eye disease.

What could go wrong

This is an early Phase 1/2 trial with only 100 participants, so results are preliminary. The injection procedure itself carries risks like infection or corneal damage, and the treatment may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

corneal neovascularization herpes simplex virus keratitis Keratitis, Herpetic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 1 Xihu Avenue, Shangcheng District,Hangzhou, Zhejiang,China,Hangzhou, Zhejiang Completed

    RECRUITING

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••