Eye injection could stop damaging blood vessels in Herpes-Related blindness
NCT ID NCT07329686
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether injecting anti-VEGF medication directly into the cornea can safely reduce abnormal blood vessel growth caused by herpes simplex keratitis. One hundred adults will receive either the injection plus antiviral eye drops or standard antiviral drops alone. Researchers will measure changes in blood vessel area, vision, and eye clarity over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- anti-VEGF medication
- What this could lead to
- If successful, this could offer a new, targeted treatment to reduce abnormal blood vessels in the cornea and improve vision for people with herpes-related eye disease.
- What could go wrong
- This is an early Phase 1/2 trial with only 100 participants, so results are preliminary. The injection procedure itself carries risks like infection or corneal damage, and the treatment may not work for everyone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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1 Xihu Avenue, Shangcheng District,Hangzhou, Zhejiang,China,Hangzhou, Zhejiang Completed
RECRUITINGHangzhou, Zhejiang, China
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