Armored cells take on tough lymphoma in early trial

NCT ID NCT07368270

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests a new type of immune cell therapy called anti-PD1 armored CD19 CAR-T cells in 30 adults with diffuse large B-cell lymphoma that has come back or not responded to treatment. The cells are designed to better attack cancer and resist exhaustion. The main goal is to check safety and find the right dose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Anti-PD1 armored CD19 CAR-T cells

What this could lead to

If successful, this could lead to a more effective treatment for hard-to-treat lymphoma by helping the immune system fight cancer longer.

What could go wrong

This is an early Phase 1 trial with only 30 people, so safety and effectiveness are not yet proven. Side effects like cytokine release syndrome or nerve problems are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma relapsed/refractory diffuse large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Suzhou Hongci Hematology Hospital

    RECRUITING

    Suzhou, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••