Could your own antibodies make a respiratory infection worse?

NCT ID NCT05536219

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether certain autoantibodies that block the body's natural antiviral defenses lead to higher viral levels and slower recovery in severe respiratory infections like flu, RSV, and COVID-19. Researchers will measure viral load changes over a week in 360 ICU patients (adults and children) to understand why some people develop severe illness. The goal is to uncover immune system weaknesses that could guide future treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hopital Lyon Sud

    RECRUITING

    Pierre-Bénite, Rhone, 69110, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Croix Rousse

    RECRUITING

    Lyon, Rhône, 69004, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Femme Mère et enfant

    RECRUITING

    Bron, Rhone, 69500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••