Could your own antibodies make a respiratory infection worse?
NCT ID NCT05536219
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study investigates whether certain autoantibodies that block the body's natural antiviral defenses lead to higher viral levels and slower recovery in severe respiratory infections like flu, RSV, and COVID-19. Researchers will measure viral load changes over a week in 360 ICU patients (adults and children) to understand why some people develop severe illness. The goal is to uncover immune system weaknesses that could guide future treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SEVERE RESPIRATORY INFECTIONS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hopital Lyon Sud
RECRUITINGPierre-Bénite, Rhone, 69110, France
-
Hôpital Croix Rousse
RECRUITINGLyon, Rhône, 69004, France
-
Hôpital Femme Mère et enfant
RECRUITINGBron, Rhone, 69500, France