New cancer pill enters first human tests for advanced solid tumors
NCT ID NCT06328439
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial is testing an experimental oral drug called ANS014004 in 40 adults with advanced solid tumors that have not responded to standard treatments. The study has two parts: first, finding the safest dose, then expanding to see if the drug can shrink tumors. The main focus is on safety and side effects, with tumor response measured every 8 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ANS014004 (an oral drug)
- What this could lead to
- If this drug is safe and shows signs of shrinking tumors, it could lead to a new treatment option for people with advanced solid cancers that have stopped responding to standard therapies.
- What could go wrong
- This is a very early Phase 1 trial with only 40 participants, so the main goal is safety, not effectiveness. The drug may not work or could cause side effects, and it will take years of further testing before it might become available.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED OR METASTATIC SOLID TUMORS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Shanghai Chest Hospital
Shanghai, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new Immune-Boosting pill make immunotherapy work better against Hard-to-Treat tumors?
- Can a new drug shrink Hard-to-Treat cancers? an early trial seeks answers
- Can a new drug ASP388B take on advanced solid tumors?
- Can a new infusion drug tame advanced solid tumors?
- New antibody drug takes aim at Hard-to-Treat cancers
- New drug duo aims to shrink hard-to-treat tumors