Pupil differences in ICU patients may reveal hidden brain clues
NCT ID NCT06964997
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how often new pupil differences (one pupil larger than the other or not reacting normally) appear in adult intensive care patients. Researchers will review medical records from 2013 to 2024 to see what these changes mean for diagnosis, treatment, and patient outcomes. The goal is to better understand when a pupil change signals a serious problem and when it does not.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If patterns emerge, this could help doctors better understand when a pupil change signals a serious brain issue versus a harmless finding.
- What could go wrong
- This is a retrospective review of medical records, not a controlled experiment. It can show links but cannot prove cause and effect.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Basel, Clinic for Intensive Care Medicine
Basel, Canton of Basel-City, 4031, Switzerland