New drug trial offers hope for stubborn skin lupus

NCT ID NCT06015737

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a drug called anifrolumab can help adults with chronic skin lupus who haven't gotten better with standard treatments. About 302 participants will receive either the drug or a placebo for 24 weeks, followed by an open period where everyone gets the drug. The main goal is to see if the drug can significantly reduce skin rash severity and improve quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Phone: •••-•••-•••• Email: •••••@•••••

Locations

Research Site
WITHDRAWN

Glendale, Arizona, 85306, United States
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Phoenix, Arizona, 85028, United States
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Covina, California, 91722, United States
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Fountain Valley, California, 92708, United States
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La Jolla, California, 92037, United States
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Los Angeles, California, 90045, United States
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Los Angeles, California, 90089, United States
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Orange, California, 92868, United States
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Orange, California, 92868, United States
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San Francisco, California, 94143, United States
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Aurora, Colorado, 80045, United States
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Denver, Colorado, 80230, United States
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New Haven, Connecticut, 06519, United States
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Washington D.C., District of Columbia, 20037, United States
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Fort Lauderdale, Florida, 33309, United States
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WITHDRAWN

Miami, Florida, 33136, United States
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TERMINATED

Miami, Florida, 33174, United States
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Plantation, Florida, 33324, United States
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Chicago, Illinois, 60611, United States
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Chicago, Illinois, 60637, United States
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Indianapolis, Indiana, 46202, United States
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Murray, Kentucky, 42071, United States
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Baltimore, Maryland, 21287, United States
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Boston, Massachusetts, 02114, United States
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Boston, Massachusetts, 02115-5817, United States
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Ann Arbor, Michigan, 48103, United States
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Ann Arbor, Michigan, 48109, United States
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Bloomfield Hills, Michigan, 48302, United States
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Rochester, Minnesota, 55905, United States
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Omaha, Nebraska, 68198-5885, United States
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Midland Park, New Jersey, 07432, United States
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Brooklyn, New York, 11201, United States
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New York, New York, 10016, United States
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New York, New York, 10028, United States
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Rochester, New York, 14642, United States
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Chapel Hill, North Carolina, 27516, United States
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Charlotte, North Carolina, 28207, United States
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Statesville, North Carolina, 28625, United States
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Cleveland, Ohio, 44124, United States
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Cleveland, Ohio, 44195, United States
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Portland, Oregon, 97239, United States
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Philadelphia, Pennsylvania, 19104, United States
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Providence, Rhode Island, 02903, United States
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Charleston, South Carolina, 29425, United States
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Summerville, South Carolina, 29486, United States
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Dallas, Texas, 75390-8843, United States
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Galveston, Texas, 77555, United States
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Mesquite, Texas, 75150, United States
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Charlottesville, Virginia, 22903, United States
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Roanoke, Virginia, 24016, United States
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Seattle, Washington, 98105, United States
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Ciudad de Buenos Aires, 1221, Argentina
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Córdoba, 5000, Argentina
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Córdoba, X5004BAL, Argentina
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Quilmes, 1878, Argentina
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Rosario, S2000PBJ, Argentina
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San Miguel, 1663, Argentina
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Clayton, 3168, Australia
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Kogarah, 3168, Australia
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Malvern, 3144, Australia
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Melbourne, 3004, Australia
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Mitcham, 3132, Australia
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Westmead, 2145, Australia
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Woolloongabba, 04102, Australia
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Graz, 8036, Austria
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Innsbruck, 6020, Austria
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Linz, 4020, Austria
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Sankt Pölten, 3100, Austria
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Vienna, 1130, Austria
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Brussels, 1200, Belgium
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Belo Horizonte, 30130-100, Brazil
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Belo Horizonte, 30150-221, Brazil
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Porto Alegre, 90035903, Brazil
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Rio de Janeiro, 22470-220, Brazil
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Salvador, 40150-150, Brazil
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São Paulo, 05403-000, Brazil
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Sofia, 1463, Bulgaria
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Sofia, 1528, Bulgaria
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WITHDRAWN

Sofia, 1606, Bulgaria
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TERMINATED

Sofia, 1784, Bulgaria
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WITHDRAWN

Sofia, 1784, Bulgaria
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RECRUITING

Vancouver, British Columbia, V5Z 1M9, Canada
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Hamilton, Ontario, L8N 3Z5, Canada
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WITHDRAWN

Newmarket, Ontario, L3Y 5G8, Canada
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Toronto, Ontario, M5T 2S8, Canada
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Osorno, 200025, Chile
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Santiago, 130021, Chile
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Santiago, 7500571, Chile
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Santiago, 8420383, Chile
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Baotou, 14010, China
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Beijing, 100029, China
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Beijing, 100043, China
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Beijing, 100050, China
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Changchun, 130021, China
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Changsha, 410011, China
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Chengdu, 610021, China
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Chongqing, 400016, China
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Dongguan, 523059, China
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Guangzhou, 510120, China
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Hangzhou, 310003, China
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Heilongjiang, 150086, China
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Jinan, 250022, China
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Kunming, 650101, China
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Nanchang, 330006, China
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NOT_YET_RECRUITING

Nanjing, 210042, China
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Shanghai, 200025, China
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Shanghai, 200443, China
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Shenzhen, 518020, China
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Shenzhen, 518052, China
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Shenzhen, 518053, China
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Shijiazhuang, 050000, China
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Ürümqi, CN-830004, China
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Wuhan, 430060, China
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Zhuzhou, 412007, China
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WITHDRAWN

Barranquilla, 01800, Colombia
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RECRUITING

Barranquilla, 080020, Colombia
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Bogotá, 110221, Colombia
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WITHDRAWN

Chía, 250001, Colombia
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Aarhus, 641-8510, Denmark
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Copenhagen, 2100, Denmark
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Bois-Guillaume, 76031, France
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Bordeaux, 33075, France
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Chambray-lès-Tours, 37170, France
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Dijon, 21000, France
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Lille, 59037, France
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Lyon, 69437, France
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Montivilliers, 76290, France
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Nantes, 44000, France
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WITHDRAWN

Nice, 06200, France
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Paris, 75010, France
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Paris, 75013, France
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Paris, 75014, France
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Paris, 75970, France
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Poitiers, 86000, FR, France
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Toulouse, 31059, France
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Berlin, 10117, Germany
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Bochum, 44791, Germany
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Dresden, 01307, Germany
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Erlangen, 91054, Germany
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Essen, 45147, Germany
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NOT_YET_RECRUITING

Freiburg im Breisgau, 79104, Germany
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WITHDRAWN

Hamburg, 20251, Germany
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Hanover, 30625, Germany
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Kiel, 24105, Germany
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Leipzig, 04103, Germany
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Mainz, 55131, Germany
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Marburg, 35043, Germany
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Regensburg, 93053, Germany
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Wuppertal, 42283, Germany
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WITHDRAWN

Athens, 11525, Greece
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Athens, 11527, GR, Greece
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Athens, 12462, Greece
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Athens, 15125, Greece
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Athens, 16121, Greece
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Brescia, 25123, Italy
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Cona, 44124, Italy
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Florence, 50121, Italy
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WITHDRAWN

Marche, 60126, Italy
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Milan, 20132, Italy
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Napoli, 80138, Italy
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Reggio Emilia, 42123, Italy
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Roma, 00144, Italy
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Rome, 00168, Italy
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Bunkyō City, 113-8431, Japan
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Chūōku, 104-8560, Japan
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Fukuoka, 812-8582, Japan
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Kanazawa, 920-8641, Japan
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Kita-gun, 761-0793, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 457-8510, Japan
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Nagoya, 467-8602, Japan
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Okayama, 700-8558, Japan
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Omura-shi, 856-8562, Japan
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WITHDRAWN

Ono, 675-1392, Japan
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Osaka, 545-8586, Japan
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Sapporo, 060-8648, Japan
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Suita, 565-0871, Japan
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tabashi City, 173-8606, Japan
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Wakayama, 641-8510, Japan
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Yokohama, 232-0024, Japan
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Yokohama, 245-8575, Japan
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Yotsukaido-shi, 284-0003, Japan
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Cuernavaca, 62170, Mexico
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Guadalajara, 44340, Mexico
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Guadalajara, 44610, Mexico
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Guadalajara, 44638, Mexico
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Guadalajara, 44690, Mexico
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Mexico City, 07760, Mexico
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San Luis Potosí City, 78213, Mexico
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Veracruz, 91910, Mexico
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Zapopan, 45070, Mexico
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Amsterdam, 1105 AZ, Netherlands
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Breda, 4818 CK, Netherlands
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Nijmegen, 6525 GA, Netherlands
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Rotterdam, 3015 GD, Netherlands
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Hamilton, 3204, New Zealand
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Papatoetoe, 2025, New Zealand
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Iloilo City, 5000, Philippines
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Lipa, 4217, Philippines
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Manila, 1000, Philippines
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Gdynia, 10-229, Poland
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Katowice, 40-851, Poland
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Kielce, 25-316, Poland
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Olsztyn, 30-229, Poland
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Ossy, 40-027, Poland
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Poznan, 60-529, Poland
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Rzeszów, 35-055, Poland
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Warsaw, 02-507, Poland
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Warsaw, 02-637, Poland
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Warsaw, 02-953, Poland
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Braga, 4710-243, Portugal
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Coimbra, 3004-561, Portugal
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Lisbon, 1649-035, Portugal
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Porto, 4099-001, Portugal
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Bucharest, 011774, Romania
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Bucharest, 020125, Romania
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Craiova, 200061, Romania
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Iași, 700291, Romania
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Târgu Mureş, 540342, Romania
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Belgrade, 11000, Serbia
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NOT_YET_RECRUITING

Belgrade, 11000, Serbia
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Belgrade, 11000, Serbia
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Kragujevac, 34000, Serbia
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Košice, 04001, Slovakia
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Piešťany, 92101, Slovakia
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Piešťany, 92101, Slovakia
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Svidník, 089 01, Slovakia
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Cape Town, 7500, South Africa
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Johannesburg, 2193, South Africa
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Seoul, 03080, South Korea
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Seoul, 06591, South Korea
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Seoul, 06973, South Korea
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A Coruña, 15006, Spain
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Barcelona, 08025, Spain
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Barcelona, 8035, Spain
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Castellon, 12004, Spain
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Granada, 18012, Spain
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L'Hospitalet de Llobregat, 08907, Spain
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Las Palmas de Gran Canaria, 35010, Spain
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Madrid, 28006, Spain
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Madrid, 28034, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Majadahonda, 28222, Spain
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Salamanca, 37007, Spain
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Seville, 41014, Spain
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Valencia, 46014, Spain
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Valencia, 46017, Spain
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Vigo, 36200, Spain
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Kaohsiung City, 83301, Taiwan
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Taichung, 404, Taiwan
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Taipei, 10449, Taiwan
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Taipei, 11217, Taiwan
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Bangkok, 10330, Thailand
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Bangkok, 10700, Thailand
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Hat Yai, 90110, Thailand
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Khlong Luang, 12120, Thailand
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Khon Kaen, 40002, Thailand
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Cordaleo, 35575, Turkey (Türkiye)
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Istanbul, 34098, Turkey (Türkiye)
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NOT_YET_RECRUITING

Istanbul, 34668, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Samsun, 55270, Turkey (Türkiye)
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Cambridge, CB2 0QQ, United Kingdom
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Leeds, LS2 9JT, United Kingdom
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London, NW1 2PG, United Kingdom
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London, NW3 2QG, United Kingdom
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London, SE1 7EH, United Kingdom
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London, SE5 9RS, United Kingdom
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Newcastle upon Tyne, NE1 4LP, United Kingdom

Conditions

Explore the condition pages connected to this study.

CUTANEOUS LUPUS ERYTHEMATOSUS