New lupus injection aims to tame overactive immune system

NCT ID NCT04877691

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a weekly injection called anifrolumab can help control disease activity in adults with moderate-to-severe lupus who are already on standard treatments. About 360 participants will receive either the drug or a placebo for one year to see if it reduces lupus symptoms and allows for lower steroid doses. The goal is to better manage this chronic autoimmune disease where the body's immune system attacks its own tissues.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Birmingham, Alabama, 35233, United States
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Paradise Valley, Arizona, 85253, United States
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Phoenix, Arizona, 85032, United States
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El Cajon, California, 92020, United States
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Fullerton, California, 92835, United States
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Hemet, California, 92543, United States
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La Mesa, California, 91942, United States
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Los Angeles, California, 90095, United States
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Menifee, California, 92586, United States
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Upland, California, 91786, United States
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Aurora, Colorado, 80045, United States
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Brandon, Florida, 33511, United States
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Clearwater, Florida, 33759, United States
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Clearwater, Florida, 33765, United States
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Miami, Florida, 33180, United States
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Tampa, Florida, 33613, United States
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Tampa, Florida, 33614, United States
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Idaho Falls, Idaho, 83404, United States
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Flint, Michigan, 48504, United States
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Lansing, Michigan, 48911, United States
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Newark, New Jersey, 07103, United States
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Las Cruces, New Mexico, 88011, United States
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Brooklyn, New York, 11201, United States
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Manhasset, New York, 11030, United States
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New York, New York, 10032, United States
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Potsdam, New York, 13676, United States
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Charlotte, North Carolina, 28203, United States
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Charlotte, North Carolina, 28204, United States
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Oklahoma City, Oklahoma, 73104, United States
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Pittsburgh, Pennsylvania, 15224, United States
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Reading, Pennsylvania, 19610, United States
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Memphis, Tennessee, 38119, United States
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Grapevine, Texas, 76051, United States
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Ciudad de Buenos Aires, C1431FWO, Argentina
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La Plata, 1900, Argentina
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Mendoza, 5500, Argentina
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Pergamino, B2700CPM, Argentina
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Quilmes, B1878GEG, Argentina
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Rosario, S2000PBJ, Argentina
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Salta, A4400ANW, Argentina
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San Isidro, 1643, Argentina
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San Juan, 5400, Argentina
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San Miguel de Tucumán, 4000, Argentina
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San Miguel de Tucumán, T4000AXL, Argentina
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San Miguel de Tucumán, T4000ICL, Argentina
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Kardzhali, 6600, Bulgaria
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Pleven, 5800, Bulgaria
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Plovdiv, 4003, Bulgaria
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Sevlievo, 5400, Bulgaria
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Sofia, 1407, Bulgaria
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Sofia, 1431, Bulgaria
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Sofia, 1606, Bulgaria
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Sofia, 1784, Bulgaria
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Sofia, 1797, Bulgaria
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Osorno, 5290000, Chile
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Santiago, 7500010, Chile
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Santiago, 7500571, Chile
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Santiago, 7500588, Chile
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Santiago, 7500710, Chile
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Santiago, 7501126, Chile
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Santiago, 8320000, Chile
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Valdivia, 5090000, Chile
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Barranquilla, 080002, Colombia
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Barranquilla, 080020, Colombia
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Bogotá, 110221, Colombia
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Bucaramanga, 680003, Colombia
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Chía, 250001, Colombia
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Montería, 230002, Colombia
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Berlin, 10117, Germany
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Cologne, 50937, Germany
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Leipzig, 04103, Germany
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Tübingen, 72076, Germany
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Budapest, 1027, Hungary
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Budapest, 1097, Hungary
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Gyula, 5700, Hungary
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Székesfehérvár, 8000, Hungary
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Veszprém, 8200, Hungary
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Chiba, 260-8712, Japan
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Chūōku, 104-8560, Japan
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Hamamatsu, 431-3192, Japan
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Hiroshima, 734-8551, Japan
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Itabashi-ku, 173-8610, Japan
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Kita-gun, 761-0793, Japan
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Kitakyushu-shi, 807-8555, Japan
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Meguro-ku, 152-8902, Japan
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Meguro-ku, 153-8515, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 457-8510, Japan
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Nagoya, 460-0001, Japan
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Okayama, 700-8607, Japan
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Sagamihara-shi, 252-0375, Japan
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Sasebo-shi, 857-1195, Japan
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Sendai, 980-8574, Japan
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Shinjuku-ku, 160-8582, Japan
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Chihuahua City, 31000, Mexico
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Culiacán, 80000, Mexico
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Durango, 43080, Mexico
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Guadalajara, 44130, Mexico
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Guadalajara, 44650, Mexico
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Guadalajara, 44950, Mexico
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Mexicali, 21200, Mexico
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Mérida, 97000, Mexico
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Mérida, 97070, Mexico
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México, 03100, Mexico
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México, 03720, Mexico
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México, 06700, Mexico
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Quezon City, 1118, Philippines
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Katowice, 40-081, Poland
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Kościan, 64-000, Poland
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Krakow, 30-033, Poland
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Krakow, 30-363, Poland
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Krakow, 30-510, Poland
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Lodz, 90-368, Poland
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Lublin, 20-607, Poland
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Nowa Sól, 67-100, Poland
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Ustroń, 43-450, Poland
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Warsaw, 00-874, Poland
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Warsaw, 02-118, Poland
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Warsaw, 02-691, Poland
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Wroclaw, 50-088, Poland
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Wroclaw, 50-244, Poland
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Barcelona, 08036, Spain
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Barcelona, 8003, Spain
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Barcelona, 8035, Spain
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Madrid, 28702, Spain
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Santiago de Compostela, 15706, Spain
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Seville, 41010, Spain
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Valencia, 46026, Spain
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Muang, 50200, Thailand
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Rachathewi, 10400, Thailand
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Kyiv, 01601, Ukraine
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Kyiv, 02091, Ukraine
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Kyiv, 04050, Ukraine
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Odesa, 65025, Ukraine
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Vinnytsia, 21001, Ukraine
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Vinnytsia, 21029, Ukraine
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Zaporizhzhia, 69600, Ukraine
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Doncaster, DN2 5LT, United Kingdom
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Leeds, LS7 4SA, United Kingdom
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London, SE1 9RT, United Kingdom

Conditions

Explore the condition pages connected to this study.

SYSTEMIC LUPUS ERYTHEMATOSUS