New hope for stubborn lupus skin rash: drug trial underway

NCT ID NCT06015737

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study tests a drug called anifrolumab for people with lupus-related skin rashes that haven't improved with standard treatments. About 306 adults will receive either the drug or a placebo to see if it reduces rash severity by 70%. The goal is to control the disease, not cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Phoenix, Arizona, 85028, United States
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Covina, California, 91722, United States
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La Jolla, California, 92037, United States
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Los Angeles, California, 90045, United States
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Los Angeles, California, 90089, United States
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Orange, California, 92868, United States
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San Francisco, California, 94143, United States
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Aurora, Colorado, 80045, United States
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New Haven, Connecticut, 06519, United States
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Washington D.C., District of Columbia, 20037, United States
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Fort Lauderdale, Florida, 33309, United States
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Miami, Florida, 33174, United States
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Plantation, Florida, 33324, United States
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Chicago, Illinois, 60611, United States
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Chicago, Illinois, 60637, United States
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Indianapolis, Indiana, 46202, United States
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Baltimore, Maryland, 21287, United States
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Boston, Massachusetts, 02114, United States
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Boston, Massachusetts, 02115-5817, United States
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Ann Arbor, Michigan, 48109, United States
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Bloomfield Hills, Michigan, 48302, United States
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Rochester, Minnesota, 55905, United States
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Omaha, Nebraska, 68198-5885, United States
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New York, New York, 10028, United States
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Rochester, New York, 14642, United States
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Charlotte, North Carolina, 28207, United States
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Statesville, North Carolina, 28625, United States
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Cleveland, Ohio, 44195, United States
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Portland, Oregon, 97239, United States
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Providence, Rhode Island, 02903, United States
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Charleston, South Carolina, 29425, United States
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Dallas, Texas, 75390-8843, United States
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Charlottesville, Virginia, 22903, United States
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Roanoke, Virginia, 24016, United States
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Ciudad de Buenos Aires, 1221, Argentina
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Córdoba, 5000, Argentina
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Córdoba, X5004BAL, Argentina
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Quilmes, 1878, Argentina
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San Miguel, 1663, Argentina
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Kogarah, 3168, Australia
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Melbourne, 3004, Australia
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Mitcham, 3132, Australia
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Westmead, 2145, Australia
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Woolloongabba, 04102, Australia
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Graz, 8036, Austria
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Innsbruck, 6020, Austria
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Linz, 4020, Austria
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Vienna, 1130, Austria
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Belo Horizonte, 30150-221, Brazil
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Porto Alegre, 90035903, Brazil
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Rio de Janeiro, 22470-220, Brazil
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Salvador, 40150-150, Brazil
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São Paulo, 05403-000, Brazil
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Sofia, 1463, Bulgaria
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Sofia, 1528, Bulgaria
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Sofia, 1784, Bulgaria
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Vancouver, British Columbia, V5Z 1M9, Canada
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Hamilton, Ontario, L8N 3Z5, Canada
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Toronto, Ontario, M5T 2S8, Canada
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Osorno, 200025, Chile
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Santiago, 130021, Chile
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Santiago, 7500571, Chile
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Changchun, 130021, China
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Changsha, 410011, China
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Chengdu, 610021, China
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Chongqing, 400016, China
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Dongguan, 523059, China
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Guangzhou, 510120, China
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Heilongjiang, 150086, China
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Jinan, 250022, China
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Shanghai, 200025, China
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Shanghai, 200443, China
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Shenzhen, 518020, China
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Shenzhen, 518052, China
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Shenzhen, 518053, China
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Ürümqi, CN-830004, China
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Zhuzhou, 412007, China
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Barranquilla, 080020, Colombia
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Bogotá, 110221, Colombia
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Aarhus, 641-8510, Denmark
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Copenhagen, 2100, Denmark
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Bois-Guillaume, 76031, France
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Dijon, 21000, France
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Lyon, 69437, France
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Montivilliers, 76290, France
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Nantes, 44000, France
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Paris, 75010, France
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Paris, 75013, France
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Paris, 75014, France
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Paris, 75970, France
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Poitiers, 86000, FR, France
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Toulouse, 31059, France
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Berlin, 10117, Germany
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Bochum, 44791, Germany
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Dresden, 01307, Germany
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Erlangen, 91054, Germany
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Essen, 45147, Germany
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Freiburg im Breisgau, 79104, Germany
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Hanover, 30625, Germany
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Kiel, 24105, Germany
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Leipzig, 04103, Germany
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Mainz, 55131, Germany
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Marburg, 35043, Germany
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Regensburg, 93053, Germany
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Wuppertal, 42283, Germany
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Athens, 12462, Greece
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Athens, 16121, Greece
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Brescia, 25123, Italy
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Cona, 44124, Italy
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Florence, 50121, Italy
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Milan, 20132, Italy
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Naples, 80138, Italy
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Reggio Emilia, 42123, Italy
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Roma, 00144, Italy
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Rome, 00168, Italy
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Chūōku, 104-8560, Japan
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Fukuoka, 812-8582, Japan
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Kanazawa, 920-8641, Japan
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Kita-gun, 761-0793, Japan
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Nagoya, 457-8510, Japan
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Nagoya, 467-8602, Japan
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tabashi City, 173-8606, Japan
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Wakayama, 641-8510, Japan
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Yokohama, 232-0024, Japan
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Guadalajara, 44340, Mexico
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Guadalajara, 44610, Mexico
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Mexico City, 07760, Mexico
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Veracruz, 91910, Mexico
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Breda, 4818 CK, Netherlands
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Rotterdam, 3015 GD, Netherlands
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Papatoetoe, 2025, New Zealand
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Iloilo City, 5000, Philippines
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Lipa, 4217, Philippines
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Manila, 1000, Philippines
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Katowice, 40-851, Poland
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Kielce, 25-316, Poland
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Ossy, 40-027, Poland
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Rzeszów, 35-055, Poland
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Warsaw, 02-637, Poland
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Braga, 4710-243, Portugal
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Lisbon, 1649-035, Portugal
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Porto, 4099-001, Portugal
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Bucharest, 020125, Romania
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Iași, 700291, Romania
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Belgrade, 11000, Serbia
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Kragujevac, 34000, Serbia
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Košice, 04001, Slovakia
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Piešťany, 92101, Slovakia
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Cape Town, 7500, South Africa
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Johannesburg, 2193, South Africa
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Seoul, 03080, South Korea
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Seoul, 06591, South Korea
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Seoul, 06973, South Korea
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Barcelona, 08025, Spain
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Barcelona, 8035, Spain
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Castellon, 12004, Spain
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Granada, 18012, Spain
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L'Hospitalet de Llobregat, 08907, Spain
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Las Palmas de Gran Canaria, 35010, Spain
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Madrid, 28006, Spain
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Madrid, 28034, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Majadahonda, 28222, Spain
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Salamanca, 37007, Spain
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Seville, 41014, Spain
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Valencia, 46014, Spain
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Valencia, 46017, Spain
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Vigo, 36200, Spain
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Kaohsiung City, 83301, Taiwan
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Taichung, 404, Taiwan
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Taipei, 10449, Taiwan
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Bangkok, 10330, Thailand
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Bangkok, 10700, Thailand
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Hat Yai, 90110, Thailand
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Khlong Luang, 12120, Thailand
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Khon Kaen, 40002, Thailand
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Cordaleo, 35575, Turkey (Türkiye)
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Istanbul, 34098, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Samsun, 55270, Turkey (Türkiye)
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Cambridge, CB2 0QQ, United Kingdom
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Leeds, LS2 9JT, United Kingdom
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London, NW1 2PG, United Kingdom
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London, NW3 2QG, United Kingdom
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London, SE1 7EH, United Kingdom
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London, SE5 9RS, United Kingdom
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Newcastle upon Tyne, NE1 4LP, United Kingdom

Conditions

Explore the condition pages connected to this study.

CUTANEOUS LUPUS ERYTHEMATOSUS