Could a common hormone beat dangerous Post-Surgery low blood pressure?

NCT ID NCT06487585

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether angiotensin II, a drug that narrows blood vessels, can safely and effectively treat dangerously low blood pressure after heart surgery. About 100 adults undergoing heart surgery with a heart-lung machine will receive the drug as a first-line treatment. Researchers will track complications like kidney injury and irregular heartbeat over 28 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Angiotensin II

What this could lead to

If successful, this could provide a new, more effective first-line option to stabilize blood pressure after heart surgery, potentially reducing serious complications like kidney injury and irregular heartbeat.

What could go wrong

This is a small, early-phase 4 trial with only 100 participants, so results may not apply to all patients. The drug may not outperform existing treatments and could have side effects like excessive blood pressure elevation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aneurysm hypotensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Maryland St. Joseph Medical Center

    RECRUITING

    Towson, Maryland, 21204, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••