Could a common hormone beat dangerous Post-Surgery low blood pressure?
NCT ID NCT06487585
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether angiotensin II, a drug that narrows blood vessels, can safely and effectively treat dangerously low blood pressure after heart surgery. About 100 adults undergoing heart surgery with a heart-lung machine will receive the drug as a first-line treatment. Researchers will track complications like kidney injury and irregular heartbeat over 28 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Angiotensin II
- What this could lead to
- If successful, this could provide a new, more effective first-line option to stabilize blood pressure after heart surgery, potentially reducing serious complications like kidney injury and irregular heartbeat.
- What could go wrong
- This is a small, early-phase 4 trial with only 100 participants, so results may not apply to all patients. The drug may not outperform existing treatments and could have side effects like excessive blood pressure elevation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Maryland St. Joseph Medical Center
RECRUITINGTowson, Maryland, 21204, United States