New combo therapies target Tough-to-Treat angiosarcoma

NCT ID NCT04339738

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is testing two different drug combinations for adults with angiosarcoma, a rare and aggressive cancer. For patients who haven't had a specific type of chemo, it compares standard chemo (paclitaxel) alone to that chemo plus an immunotherapy drug (nivolumab). For patients whose cancer has grown after that chemo, it tests a different combo of immunotherapy (nivolumab) and a targeted drug (cabozantinib). The goal is to see if these combinations can better control the cancer and stop it from growing.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Atrium Health Pineville/LCI-Pineville

Charlotte, North Carolina, 28210, United States
Banner University Medical Center - Tucson

Tucson, Arizona, 85719, United States
Cambridge Medical Center

Cambridge, Minnesota, 55008, United States
Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017, United States
Cancer Centers of Southwest Oklahoma Research

Lawton, Oklahoma, 73505, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Physician Group-Effingham

Effingham, Illinois, 62401, United States
Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938, United States
Carle at The Riverfront

Danville, Illinois, 61832, United States
Carolinas Medical Center/Levine Cancer Institute

Charlotte, North Carolina, 28203, United States
Castle Medical Center

Kailua, Hawaii, 96734, United States
Central Care Cancer Center - Bolivar

Bolivar, Missouri, 65613, United States
Central Care Cancer Center - Garden City

Garden City, Kansas, 67846, United States
Central Care Cancer Center - Great Bend

Great Bend, Kansas, 67530, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
CoxHealth South Hospital

Springfield, Missouri, 65807, United States
Dana-Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Divine Providence Hospital

Williamsport, Pennsylvania, 17754, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
FHP Health Center-Guam

Tamuning, 96913, Guam
Fairview Clinics and Surgery Center Maple Grove

Maple Grove, Minnesota, 55369, United States
Fairview Lakes Medical Center

Wyoming, Minnesota, 55092, United States
Fairview Northland Medical Center

Princeton, Minnesota, 55371, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fairview Southdale Hospital

Edina, Minnesota, 55435, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Fred Hutchinson Cancer Center

Seattle, Washington, 98109, United States
Freeman Health System

Joplin, Missouri, 64804, United States
Gibbs Cancer Center-Gaffney

Gaffney, South Carolina, 29341, United States
Gibbs Cancer Center-Pelham

Greer, South Carolina, 29651, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Hawaii Cancer Care - Westridge

‘Aiea, Hawaii, 96701, United States
Hawaii Cancer Care Inc - Waterfront Plaza

Honolulu, Hawaii, 96813, United States
Hawaii Cancer Care Inc-Liliha

Honolulu, Hawaii, 96817, United States
Hawaii Diagnostic Radiology Services LLC

Honolulu, Hawaii, 96817, United States
Health Partners Inc

Minneapolis, Minnesota, 55454, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Island Urology

Honolulu, Hawaii, 96813, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Kapiolani Medical Center for Women and Children

Honolulu, Hawaii, 96826, United States
Kuakini Medical Center

Honolulu, Hawaii, 96817, United States
LSU Health Sciences Center at Shreveport

Shreveport, Louisiana, 71103, United States
Lakeview Hospital

Stillwater, Minnesota, 55082, United States
Marshfield Medical Center - Minocqua

Minocqua, Wisconsin, 54548, United States
Marshfield Medical Center - Weston

Weston, Wisconsin, 54476, United States
Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701, United States
Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868, United States
Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482, United States
Mary Greeley Medical Center

Ames, Iowa, 50010, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
Mayo Clinic Hospital in Arizona

Phoenix, Arizona, 85054, United States
Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
McFarland Clinic - Ames

Ames, Iowa, 50010, United States
McFarland Clinic - Boone

Boone, Iowa, 50036, United States
McFarland Clinic - Jefferson

Jefferson, Iowa, 50129, United States
McFarland Clinic - Marshalltown

Marshalltown, Iowa, 50158, United States
McFarland Clinic - Trinity Cancer Center

Fort Dodge, Iowa, 50501, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Mercy Clinic-Rolla-Cancer and Hematology

Rolla, Missouri, 65401, United States
Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy Hospital Fort Smith

Fort Smith, Arkansas, 72903, United States
Mercy Hospital Joplin

Joplin, Missouri, 64804, United States
Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Hospital South

St Louis, Missouri, 63128, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mercy Hospital Washington

Washington, Missouri, 63090, United States
Mercy Infusion Center - Chippewa

St Louis, Missouri, 63109, United States
Mercy Oncology and Hematology - Clayton-Clarkson

Ballwin, Missouri, 63011, United States
Minnesota Oncology - Burnsville

Burnsville, Minnesota, 55337, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125, United States
Moffitt Cancer Center

Tampa, Florida, 33612, United States
Moffitt Cancer Center - McKinley Campus

Tampa, Florida, 33612, United States
Moffitt Cancer Center-International Plaza

Tampa, Florida, 33607, United States
Monticello Cancer Center

Monticello, Minnesota, 55362, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

New York, New York, 10032, United States
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
New Ulm Medical Center

New Ulm, Minnesota, 56073, United States
North Grove Medical Park

Spartanburg, South Carolina, 29303, United States
North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422, United States
NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201, United States
NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026, United States
NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035, United States
Northwell Health/Center for Advanced Medicine

Lake Success, New York, 11042, United States
Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134, United States
Northwestern Medicine Cancer Center Kishwaukee

DeKalb, Illinois, 60115, United States
Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States
Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045, United States
Northwestern University

Chicago, Illinois, 60611, United States
OSF Saint Anthony's Health Center

Alton, Illinois, 62002, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oregon Health and Science University

Portland, Oregon, 97239, United States
Pali Momi Medical Center

‘Aiea, Hawaii, 96701, United States
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
Parkview Regional Medical Center

Fort Wayne, Indiana, 46845, United States
Phelps Health Delbert Day Cancer Institute

Rolla, Missouri, 65401, United States
Queen's Cancer Cenrer - POB I

Honolulu, Hawaii, 96813, United States
Queen's Cancer Center - Kuakini

Honolulu, Hawaii, 96817, United States
Queen's Cancer Center - Pearlridge

‘Aiea, Hawaii, 96701, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Rice Memorial Hospital

Willmar, Minnesota, 56201, United States
Ridgeview Medical Center

Waconia, Minnesota, 55387, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Rush MD Anderson Cancer Center

Chicago, Illinois, 60612, United States
Rush-Copley Healthcare Center

Yorkville, Illinois, 60560, United States
Rush-Copley Medical Center

Aurora, Illinois, 60504, United States
SMC Center for Hematology Oncology Union

Union, South Carolina, 29379, United States
SSM Health Good Samaritan

Mount Vernon, Illinois, 62864, United States
Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379, United States
Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States
Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States
Siteman Cancer Center at Christian Hospital

St Louis, Missouri, 63136, United States
Siteman Cancer Center at Saint Peters Hospital

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center at West County Hospital

Creve Coeur, Missouri, 63141, United States
Siteman Cancer Center-South County

St Louis, Missouri, 63129, United States
Smilow Cancer Hospital Care Center - Guilford

Guilford, Connecticut, 06437, United States
Smilow Cancer Hospital Care Center - Waterford

Waterford, Connecticut, 06385, United States
Smilow Cancer Hospital Care Center - Westerly

Westerly, Rhode Island, 02891, United States
Smilow Cancer Hospital Care Center at Glastonbury

Glastonbury, Connecticut, 06033, United States
Smilow Cancer Hospital Care Center at Greenwich

Greenwich, Connecticut, 06830, United States
Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105, United States
Smilow Cancer Hospital Care Center-Fairfield

Fairfield, Connecticut, 06824, United States
Smilow Cancer Hospital Care Center-Trumbull

Trumbull, Connecticut, 06611, United States
Smilow Cancer Hospital-Derby Care Center

Derby, Connecticut, 06418, United States
Smilow Cancer Hospital-Orange Care Center

Orange, Connecticut, 06477, United States
Smilow Cancer Hospital-Torrington Care Center

Torrington, Connecticut, 06790, United States
Smilow Cancer Hospital-Waterbury Care Center

Waterbury, Connecticut, 06708, United States
Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States
Spartanburg Medical Center - Mary Black Campus

Spartanburg, South Carolina, 29307, United States
Straub Clinic and Hospital

Honolulu, Hawaii, 96813, United States
Straub Medical Center - Kahului Clinic

Kahului, Hawaii, 96732, United States
The Cancer Center of Hawaii-Liliha

Honolulu, Hawaii, 96817, United States
The Cancer Center of Hawaii-Pali Momi

‘Aiea, Hawaii, 96701, United States
The Carle Foundation Hospital

Urbana, Illinois, 61801, United States
The Queen's Medical Center - West Oahu

‘Ewa Beach, Hawaii, 96706, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
UF Health Cancer Institute - Gainesville

Gainesville, Florida, 32610, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
UPMC Hillman Cancer Center - Monroeville

Monroeville, Pennsylvania, 15146, United States
UPMC Susquehanna

Williamsport, Pennsylvania, 17701, United States
UPMC-Saint Margaret

Pittsburgh, Pennsylvania, 15215, United States
United Hospital

Saint Paul, Minnesota, 55102, United States
Unity Hospital

Fridley, Minnesota, 55432, United States
University of Arizona Cancer Center-North Campus

Tucson, Arizona, 85719, United States
University of Arizona Cancer Center-Orange Grove Campus

Tucson, Arizona, 85704, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Hawaii Cancer Center

Honolulu, Hawaii, 96813, United States
University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232, United States
University of Utah Sugarhouse Health Center

Salt Lake City, Utah, 84106, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
VCU Massey Comprehensive Cancer Center

Richmond, Virginia, 23298, United States
Vanderbilt Breast Center at One Hundred Oaks

Nashville, Tennessee, 37204, United States
Vanderbilt University/Ingram Cancer Center

Nashville, Tennessee, 37232, United States
Vanderbilt-Ingram Cancer Center Cool Springs

Franklin, Tennessee, 37067, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wilcox Memorial Hospital and Kauai Medical Clinic

Lihue, Hawaii, 96766, United States
Yale University

New Haven, Connecticut, 06520, United States
Yale-New Haven Hospital North Haven Medical Center

North Haven, Connecticut, 06473, United States

Conditions

Explore the condition pages connected to this study.

SKIN ANGIOSARCOMA SKIN RADIATION-RELATED ANGIOSARCOMA VISCERAL ANGIOSARCOMA