Could a diabetes drug ease chest pain in women with hidden heart disease?

NCT ID NCT06600178

Recruiting now Symptom relief Sponsor: University of Virginia Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This study tests whether a drug called Brezavvy (an SGLT2 inhibitor) can improve blood flow in the small heart vessels and reduce chest pain in women who have angina but no major blockages in their heart arteries. 150 women will take either the drug or a placebo for 12 weeks and undergo heart scans and questionnaires. The goal is to see if this treatment can ease symptoms and improve quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

UVA Health
RECRUITING

Charlottesville, Virginia, 22908, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

ANGINA PATIENTS WITH NON-OBSTRUCTIVE CORONARY ARTERY DISEASE CORONARY MICROVASCULAR DISEASE CORONARY MICROVASCULAR DYSFUNCTION (CMD)