New hope for blood cancer patients battling severe anemia

NCT ID NCT04455841

Summary

This study is testing a new drug called INCB000928 to see if it can help people with a serious bone marrow cancer called myelofibrosis who have severe anemia. The drug will be tested alone and in combination with an existing medication, ruxolitinib. The main goals are to find a safe dose and see if it can reduce the need for blood transfusions and improve red blood cell counts.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Azienda Ospedaliera Papa Giovanni Xxiii

    Bergamo, 24127, Italy

  • Azienda Ospedaliera Universitaria San Luigi Gonzaga Orbassano

    Orbassano, 10043, Italy

  • Azienda Ospedaliero-Universitaria Careggi (Aouc)

    Florence, 50134, Italy

  • Centre Hospitalier D'Angers

    Angers, 49033, France

  • Chiba Cancer Center

    Chiba, 260-8717, Japan

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • City of Hope Orange County

    Irvine, California, 92618, United States

  • Comitato Di Bioetica Della Fondazione Irccs Policlinico San Matteo

    Pavia, 27100, Italy

  • Duke University Medical Center, Department of Hematologic Malignancies and Cellular Therapy

    Durham, North Carolina, 27705, United States

  • Emory University - Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Emory University-Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Gifu Municipal Hospital

    Gifu, 500-8513, Japan

  • Hospital Saint Louis

    Paris, 75010, France

  • Institut Paoli Calmettes

    Marseille, 13273, France

  • Kansai Medical University Hospital

    Hirakata, 573-1191, Japan

  • Kumamoto Shinto General Hospital

    Kumamoto, 862-8655, Japan

  • Lincoln County Hospital

    Lincoln, LN2 5QY, United Kingdom

  • McGill University Jewish General Hospital

    Montreal, Quebec, H3T1E2, Canada

  • Md Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Osaka International Cancer Institute

    Osaka, 541-8567, Japan

  • Ospedale Santa Maria Della Misericordia Perugia

    Perugia, 06124, Italy

  • Prebys Cancer Center

    San Diego, California, 92103, United States

  • Princess Margaret Cancer Center

    Toronto, Ontario, M5G 2M9, Canada

  • Royal Cornwall Hospital Truro Sunrise Centre

    Truro, TR1 3LJ, United Kingdom

  • S Orsolas University Hospital Seragnoli Institute of Hematology

    Bologna, 40138, Italy

  • Stanford Cancer Center

    Palo Alto, California, 94304, United States

  • Start Midwest

    Grand Rapids, Michigan, 49546, United States

  • Tokyo Medical and Dental University Hospital

    Bunkyō City, 113-8519, Japan

  • United Lincolnshire Hospitals

    Boston, PE21 9QS, United Kingdom

  • University Hospital of Wales

    Cardiff, WLS, CF14 4XW, United Kingdom

  • Usc Norris Comprehensive Cancer Center

    Los Angeles, California, 90089, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medical Centers

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.