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Can testosterone shots relieve dry eye? new study investigates

NCT ID NCT07168265

Disease control Sponsor: Neon Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether testosterone replacement therapy can improve dry eye symptoms in men with low testosterone. Researchers measured tear quality and eye surface health in 77 men before and during treatment. The goal was to see if hormone therapy could help manage dry eye related to androgen deficiency.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
testosterone injections
What this could lead to
If successful, this could point toward a treatment for dry eye in men with low testosterone.
What could go wrong
This is a small, completed study with only 77 participants. Results may not apply to everyone, and testosterone therapy has known side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

77 people

The number who actually took part.

Started

Jan 2020

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Androgen deficiency Exclusion Criteria: * having any ocular disease, history of surgery, drop use

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Conditions

The condition(s) this trial relates to.

hypogonadism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Androgen deficiency Ocular surface disease Tear osmolarity

Contacts and locations

Locations

  • Ondokuz Mayıs University

    Samsun, Atakum, 55139, Turkey (Türkiye)

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