Could a gel prevent anal cancer in HIV patients?

NCT ID NCT05334004

First seen Feb 11, 2026 · Last updated Apr 28, 2026 · Updated 11 times

Summary

This early-stage study tests the safety of a gel containing two HIV drugs (lopinavir/ritonavir) applied inside the anus. It involves 21 adults with HIV who have high-grade anal lesions (precancerous cells). The goal is to find a safe dose and see if the gel can shrink or eliminate these lesions, potentially preventing anal cancer.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UW Digestive Health Center Anoscopy Clinic

    RECRUITING

    Madison, Wisconsin, 53705, United States

Conditions

Explore the condition pages connected to this study.