New hope to tame the storm: drug trial aims to shield patients from CAR-T's worst side effects

NCT ID NCT04148430

Summary

This study is testing if a drug called anakinra can prevent or reduce severe brain-related side effects and dangerous immune reactions in adults receiving CAR-T cell therapy for certain B-cell cancers. The goal is to make this powerful cancer treatment safer by controlling its most serious complications. Researchers are enrolling 62 adults who have relapsed B-cell leukemia or lymphoma and are scheduled to get approved CAR-T therapy.

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Contacts and locations

Locations

  • Hackensack Meridian Health (Data collection only)

    Hackensack, New Jersey, 07601, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.