New pill combo aims to fight advanced cancers that stopped responding to prior therapies
NCT ID NCT07287917
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two oral drugs, AMXT 1501 and DFMO, given alongside standard treatments for people with advanced solid tumors (breast cancer or melanoma) that have worsened after prior therapies. The goal is to find a safe dose and see if the combination helps shrink tumors or slow disease. About 92 adults will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Laguna Clinical Research Associates
RECRUITINGLaredo, Texas, 78041, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Lumi Research
RECRUITINGHouston, Texas, 77090, United States
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START Cancer Research New York-Long Island
RECRUITINGLake Success, New York, 11042, United States
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START Los Angeles
RECRUITINGLos Angeles, California, 90025, United States
Contact
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START Mountain Region
RECRUITINGWest Valley City, Utah, 84119, United States
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Skin Cancer Institute
RECRUITINGEnglewood, Colorado, 80113, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Cincinnati Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Texas-MD Anderson
RECRUITINGHouston, Texas, 77030, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Wisconsin-Madison Carbone Cancer Center
RECRUITINGMadison, Wisconsin, 53706, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vanderbilt-Ingram Cancer Institute
RECRUITINGNashville, Tennessee, 37232, United States
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Virginia Cancer Specialists-Fairfax
RECRUITINGFairfax, Virginia, 22031, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wayne State University - Barbara Ann Karmanos Cancer Institute
RECRUITINGDetroit, Michigan, 48201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact