Personalized vaccine trial aims to train immune system to fight leukemia

NCT ID NCT03679650

Summary

This early-stage study is testing the safety of a personalized cancer vaccine for people with acute myeloid leukemia (AML) who have recently had a stem cell transplant. The vaccine is made by fusing a patient's own immune cells with their leukemia cells, aiming to teach the body's immune system to recognize and attack any remaining cancer. Researchers are also testing if adding a low-dose chemotherapy drug (decitabine) makes the vaccine work better.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.