New triple therapy aims to boost remission in elderly AML patients

NCT ID NCT07469046

First seen Mar 27, 2026 · Last updated May 06, 2026 · Updated 5 times

Summary

This phase 3 trial tests whether adding homoharringtonine to the standard two-drug regimen (venetoclax and azacitidine) improves remission rates in adults aged 60-75 with newly diagnosed acute myeloid leukemia (AML). About 308 participants will be randomly assigned to receive either the two-drug or three-drug combination. The study is open-label, meaning both doctors and patients know which treatment is given, but an independent committee will review the results to reduce bias.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE MYELOID LEUKEMIA (AML) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai General Hospital

    Shanghai, Shanghai Municipality, 200080, China

    Contact

Conditions

Explore the condition pages connected to this study.