Targeted Triple-Drug combo tested in fight against aggressive leukemia

NCT ID NCT06672146

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is for older adults (or younger adults unfit for standard chemo) newly diagnosed with a specific type of acute myeloid leukemia (AML) caused by a change in the IDH2 gene. It compares two oral drug combinations to see if adding a third drug, enasidenib, helps more patients achieve a deep remission with no detectable cancer cells. The goal is to find a more effective, targeted treatment for this patient group.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Allegiance Health
RECRUITING

Jackson, Michigan, 49201, United States

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Alta Bates Summit Medical Center-Herrick Campus
RECRUITING

Berkeley, California, 94704, United States

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Augusta University Medical Center
RECRUITING

Augusta, Georgia, 30912, United States

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Banner University Medical Center - Tucson
RECRUITING

Tucson, Arizona, 85719, United States

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Benefis Sletten Cancer Institute
RECRUITING

Great Falls, Montana, 59405, United States

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Billings Clinic Cancer Center
RECRUITING

Billings, Montana, 59101, United States

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Bozeman Health Deaconess Hospital
RECRUITING

Bozeman, Montana, 59715, United States

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Cancer Hematology Centers - Flint
RECRUITING

Flint, Michigan, 48503, United States

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Carolinas Medical Center/Levine Cancer Institute
RECRUITING

Charlotte, North Carolina, 28203, United States

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Centro Comprensivo de Cancer de UPR
RECRUITING

San Juan, 00927, Puerto Rico

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Community Hospital of Anaconda
RECRUITING

Anaconda, Montana, 59711, United States

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Community Medical Center
RECRUITING

Missoula, Montana, 59804, United States

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Community Medical Center
RECRUITING

Toms River, New Jersey, 08755, United States

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Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States

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Duluth Clinic Ashland
RECRUITING

Ashland, Wisconsin, 54806, United States

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East Carolina University
RECRUITING

Greenville, North Carolina, 27834, United States

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Essentia Health - Deer River Clinic
RECRUITING

Deer River, Minnesota, 56636, United States

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Essentia Health Cancer Center
RECRUITING

Duluth, Minnesota, 55805, United States

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Essentia Health Hibbing Clinic
RECRUITING

Hibbing, Minnesota, 55746, United States

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Essentia Health Sandstone
RECRUITING

Sandstone, Minnesota, 55072, United States

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Essentia Health Virginia Clinic
RECRUITING

Virginia, Minnesota, 55792, United States

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Geisinger Medical Center
RECRUITING

Danville, Pennsylvania, 17822, United States

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Geisinger Wyoming Valley/Henry Cancer Center
RECRUITING

Wilkes-Barre, Pennsylvania, 18711, United States

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Genesee Hematology Oncology PC
SUSPENDED

Flint, Michigan, 48503, United States
Genesys Hurley Cancer Institute
RECRUITING

Flint, Michigan, 48503, United States

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Gundersen Lutheran Medical Center
RECRUITING

La Crosse, Wisconsin, 54601, United States

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Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States

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Henry Ford Macomb Hospital-Clinton Township
RECRUITING

Clinton Township, Michigan, 48038, United States

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Henry Ford Medical Center-Columbus
RECRUITING

Novi, Michigan, 48377, United States

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Henry Ford West Bloomfield Hospital
RECRUITING

West Bloomfield, Michigan, 48322, United States

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Huntsman Cancer Institute/University of Utah
RECRUITING

Salt Lake City, Utah, 84112, United States

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Kootenai Clinic Cancer Services - Post Falls
RECRUITING

Post Falls, Idaho, 83854, United States

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Kootenai Clinic Cancer Services - Sandpoint
RECRUITING

Sandpoint, Idaho, 83864, United States

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Kootenai Health - Coeur d'Alene
RECRUITING

Coeur d'Alene, Idaho, 83814, United States

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Logan Health Medical Center
RECRUITING

Kalispell, Montana, 59901, United States

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Loyola University Medical Center
RECRUITING

Maywood, Illinois, 60153, United States

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MaineHealth Cancer Care and IV Therapy - Brunswick
RECRUITING

Brunswick, Maine, 04011, United States

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MaineHealth Cancer Care and IV Therapy - South Portland
RECRUITING

South Portland, Maine, 04106, United States

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MaineHealth Maine Medical Center - Portland
RECRUITING

Portland, Maine, 04102, United States

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Marshfield Medical Center - Weston
RECRUITING

Weston, Wisconsin, 54476, United States

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Marshfield Medical Center-River Region at Stevens Point
RECRUITING

Stevens Point, Wisconsin, 54482, United States

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Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States

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Miami Cancer Institute
RECRUITING

Miami, Florida, 33176, United States

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Mid Coast Hospital
RECRUITING

Brunswick, Maine, 04011, United States

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Mills Health Center
RECRUITING

San Mateo, California, 94401, United States

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Monmouth Medical Center
RECRUITING

Long Branch, New Jersey, 07740, United States

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NorthShore University HealthSystem-Evanston Hospital
RECRUITING

Evanston, Illinois, 60201, United States

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NorthShore University HealthSystem-Glenbrook Hospital
RECRUITING

Glenview, Illinois, 60026, United States

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NorthShore University HealthSystem-Highland Park Hospital
RECRUITING

Highland Park, Illinois, 60035, United States

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Northwestern Medicine Cancer Center Delnor
RECRUITING

Geneva, Illinois, 60134, United States

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Northwestern Medicine Cancer Center Kishwaukee
RECRUITING

DeKalb, Illinois, 60115, United States

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Northwestern Medicine Cancer Center Warrenville
RECRUITING

Warrenville, Illinois, 60555, United States

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Northwestern Medicine Glenview Outpatient Center
RECRUITING

Glenview, Illinois, 60026, United States

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Northwestern Medicine Grayslake Outpatient Center
RECRUITING

Grayslake, Illinois, 60030, United States

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Northwestern Medicine Lake Forest Hospital
RECRUITING

Lake Forest, Illinois, 60045, United States

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Northwestern Medicine Orland Park
RECRUITING

Orland Park, Illinois, 60462, United States

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Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

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OSF Saint Francis Hospital and Medical Group
RECRUITING

Escanaba, Michigan, 49829, United States

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Oregon Health and Science University
RECRUITING

Portland, Oregon, 97239, United States

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Our Lady of The Lake
RECRUITING

Baton Rouge, Louisiana, 70808, United States

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Our Lady of the Lake Physician Group
RECRUITING

Baton Rouge, Louisiana, 70808, United States

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Park Nicollet Clinic - Saint Louis Park
RECRUITING

Saint Louis Park, Minnesota, 55416, United States

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Prisma Health Cancer Institute - Butternut
RECRUITING

Greenville, South Carolina, 29605, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Prisma Health Cancer Institute - Easley
RECRUITING

Easley, South Carolina, 29640, United States

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Prisma Health Cancer Institute - Eastside
RECRUITING

Greenville, South Carolina, 29615, United States

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Prisma Health Cancer Institute - Faris
RECRUITING

Greenville, South Carolina, 29605, United States

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Prisma Health Cancer Institute - Greer
RECRUITING

Greer, South Carolina, 29650, United States

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Prisma Health Cancer Institute - Seneca
RECRUITING

Seneca, South Carolina, 29672, United States

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Prisma Health Cancer Institute - Spartanburg
RECRUITING

Boiling Springs, South Carolina, 29316, United States

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Regions Hospital
RECRUITING

Saint Paul, Minnesota, 55101, United States

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Rhode Island Hospital
RECRUITING

Providence, Rhode Island, 02903, United States

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Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States

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Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States

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Saint Alphonsus Cancer Care Center-Nampa
RECRUITING

Nampa, Idaho, 83687, United States

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Saint Barnabas Medical Center
RECRUITING

Livingston, New Jersey, 07039, United States

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Saint Luke's Cancer Institute - Boise
RECRUITING

Boise, Idaho, 83712, United States

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Saint Luke's Cancer Institute - Fruitland
RECRUITING

Fruitland, Idaho, 83619, United States

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Saint Luke's Cancer Institute - Meridian
RECRUITING

Meridian, Idaho, 83642, United States

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Saint Luke's Cancer Institute - Nampa
RECRUITING

Nampa, Idaho, 83687, United States

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Saint Vincent Hospital Cancer Center Green Bay
RECRUITING

Green Bay, Wisconsin, 54301, United States

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Saint Vincent Hospital Cancer Center at Oconto Falls
RECRUITING

Oconto Falls, Wisconsin, 54154, United States

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Saint Vincent Hospital Cancer Center at Saint Mary's
RECRUITING

Green Bay, Wisconsin, 54303, United States

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Saint Vincent Hospital Cancer Center at Sheboygan
RECRUITING

Sheboygan, Wisconsin, 53081, United States

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Saint Vincent Hospital Cancer Center at Sturgeon Bay
RECRUITING

Sturgeon Bay, Wisconsin, 54235-1495, United States

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San Juan City Hospital
RECRUITING

San Juan, 00936, Puerto Rico

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Sheboygan Physicians Group
RECRUITING

Sheboygan, Wisconsin, 53081, United States

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Swedish Cancer Institute-Edmonds
RECRUITING

Edmonds, Washington, 98026, United States

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Swedish Cancer Institute-Issaquah
RECRUITING

Issaquah, Washington, 98029, United States

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Swedish Medical Center-First Hill
RECRUITING

Seattle, Washington, 98122, United States

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The James Graham Brown Cancer Center at University of Louisville
RECRUITING

Louisville, Kentucky, 40202, United States

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Thomas Jefferson University Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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Trinity Health IHA Medical Group Hematology Oncology - Brighton
RECRUITING

Brighton, Michigan, 48114, United States

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Trinity Health IHA Medical Group Hematology Oncology - Canton
RECRUITING

Canton, Michigan, 48188, United States

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Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
RECRUITING

Chelsea, Michigan, 48118, United States

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Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
RECRUITING

Ypsilanti, Michigan, 48197, United States

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Trinity Health Saint Joseph Mercy Oakland Hospital
RECRUITING

Pontiac, Michigan, 48341, United States

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Trinity Health Saint Mary Mercy Livonia Hospital
RECRUITING

Livonia, Michigan, 48154, United States

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Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States

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UC Comprehensive Cancer Center at Silver Cross
RECRUITING

New Lenox, Illinois, 60451, United States

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UChicago Medicine Northwest Indiana
RECRUITING

Crown Point, Indiana, 46307, United States

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University of Arizona Cancer Center-North Campus
RECRUITING

Tucson, Arizona, 85719, United States

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University of Arkansas for Medical Sciences
RECRUITING

Little Rock, Arkansas, 72205, United States

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University of Chicago Comprehensive Cancer Center
RECRUITING

Chicago, Illinois, 60637, United States

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University of Chicago Medicine-Orland Park
RECRUITING

Orland Park, Illinois, 60462, United States

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University of New Mexico Cancer Center
RECRUITING

Albuquerque, New Mexico, 87106, United States

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University of Oklahoma Health Sciences Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States

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University of Pittsburgh Cancer Institute (UPCI)
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

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University of Rochester
RECRUITING

Rochester, New York, 14642, United States

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UofL Health Medical Center Northeast
RECRUITING

Louisville, Kentucky, 40245, United States

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VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States

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Wake Forest University Health Sciences
RECRUITING

Winston-Salem, North Carolina, 27157, United States

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William S Middleton VA Medical Center
RECRUITING

Madison, Wisconsin, 53705, United States

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Conditions

Explore the condition pages connected to this study.

ACUTE MYELOID LEUKEMIA