New drug combo tested to fight leukemia in seniors

NCT ID NCT00658814

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study tested a combination of two drugs, azacitidine and gemtuzumab ozogamicin, to treat older adults with a type of blood cancer called acute myeloid leukemia (AML). The goal was to see if this combination was safe and effective enough to put patients into remission and warrant a larger, more definitive trial. The study enrolled 133 patients aged 60 and older who had not received prior treatment for their AML.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
AdventHealth Shawnee Mission

Shawnee Mission, Kansas, 66204, United States
Adventist Medical Center

Portland, Oregon, 97216, United States
Advocate Sherman Hospital

Elgin, Illinois, 60123, United States
Allegiance Health

Jackson, Michigan, 49201, United States
AnMed Health Hospital

Anderson, South Carolina, 29621, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Associates In Womens Health

Wichita, Kansas, 67208, United States
Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Berdeaux, Donald MD (UIA Investigator)

Great Falls, Montana, 59405, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Blanchard Valley Hospital

Findlay, Ohio, 45840, United States
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
Bronson Battle Creek

Battle Creek, Michigan, 49017, United States
Cancer Care Center at Island Hospital

Anacortes, Washington, 98221, United States
Cancer Care Northwest - Spokane South

Spokane, Washington, 99202, United States
Cancer Center of Kansas - Chanute

Chanute, Kansas, 66720, United States
Cancer Center of Kansas - Dodge City

Dodge City, Kansas, 67801, United States
Cancer Center of Kansas - El Dorado

El Dorado, Kansas, 67042, United States
Cancer Center of Kansas - Fort Scott

Fort Scott, Kansas, 66701, United States
Cancer Center of Kansas - Newton

Newton, Kansas, 67114, United States
Cancer Center of Kansas - Parsons

Parsons, Kansas, 67357, United States
Cancer Center of Kansas - Pratt

Pratt, Kansas, 67124, United States
Cancer Center of Kansas - Salina

Salina, Kansas, 67401, United States
Cancer Center of Kansas - Wellington

Wellington, Kansas, 67152, United States
Cancer Center of Kansas - Wichita

Wichita, Kansas, 67214, United States
Cancer Center of Kansas - Winfield

Winfield, Kansas, 67156, United States
Cancer Center of Kansas-Independence

Independence, Kansas, 67301, United States
Cancer Center of Kansas-Kingman

Kingman, Kansas, 67068, United States
Cancer Center of Kansas-Liberal

Liberal, Kansas, 67905, United States
Cancer Center of Kansas-Wichita Medical Arts Tower

Wichita, Kansas, 67208, United States
Cancer Research Consortium of West Michigan NCORP

Grand Rapids, Michigan, 49503, United States
Clackamas Radiation Oncology Center

Clackamas, Oregon, 97015, United States
Cleveland Clinic Akron General

Akron, Ohio, 44307, United States
Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center

Wilmington, Ohio, 45177, United States
Columbus NCI Community Oncology Research Program

Columbus, Ohio, 43215, United States
Community Medical Center

Missoula, Montana, 59804, United States
Corewell Health Dearborn Hospital

Dearborn, Michigan, 48124, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
Cotton O'Neil Cancer Center / Stormont Vail Health

Topeka, Kansas, 66606, United States
Dayton NCI Community Oncology Research Program

Dayton, Ohio, 45459, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Doctors Hospital

Columbus, Ohio, 43228, United States
Evergreen Hematology and Oncology PS

Spokane, Washington, 99218, United States
Fairfield Medical Center

Lancaster, Ohio, 43130, United States
Franciscan Saint Francis Health-Beech Grove

Beech Grove, Indiana, 46107, United States
Fred Hutchinson Cancer Center

Seattle, Washington, 98109, United States
Genesis Healthcare System Cancer Care Center

Zanesville, Ohio, 43701, United States
Genesys Regional Medical Center-West Flint Campus

Flint, Michigan, 48532, United States
Glacier Oncology PLLC

Kalispell, Montana, 59901, United States
Good Samaritan Hospital - Dayton

Dayton, Ohio, 45406, United States
Grady Memorial Hospital

Delaware, Ohio, 43015, United States
Grandview Hospital

Dayton, Ohio, 45405, United States
Grant Medical Center

Columbus, Ohio, 43215, United States
Great Falls Clinic

Great Falls, Montana, 59405, United States
Greene Memorial Hospital

Xenia, Ohio, 45385, United States
Guardian Oncology and Center for Wellness

Missoula, Montana, 59804, United States
Harborview Medical Center

Seattle, Washington, 98104, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo

Poulsbo, Washington, 98370, United States
Heartland Cancer Research NCORP

Decatur, Illinois, 62526, United States
Heartland Hematology and Oncology Associates Incorporated

Kansas City, Missouri, 64118, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Hematology/Oncology Clinic PLLC

Baton Rouge, Louisiana, 70809, United States
Henry Ford Health Providence Southfield Hospital

Southfield, Michigan, 48075, United States
Henry Ford Health Saint John Hospital

Detroit, Michigan, 48236, United States
Henry Ford Health Warren Hospital

Warren, Michigan, 48093, United States
Highline Medical Center-Main Campus

Burien, Washington, 98166, United States
Hospital District Sixth of Harper County

Anthony, Kansas, 67003, United States
Hurley Medical Center

Flint, Michigan, 48503, United States
Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336, United States
Kaiser Permanente Washington

Seattle, Washington, 98112, United States
Kalispell Medical Oncology

Kalispell, Montana, 59901, United States
Kansas City NCI Community Oncology Research Program

Prairie Village, Kansas, 66208, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Knox Community Hospital

Mount Vernon, Ohio, 43050, United States
Lake Huron Medical Center

Port Huron, Michigan, 48060, United States
Lawrence Memorial Hospital

Lawrence, Kansas, 66044, United States
Legacy Emanuel Hospital and Health Center

Portland, Oregon, 97227, United States
Legacy Good Samaritan Hospital and Medical Center

Portland, Oregon, 97210, United States
Legacy Meridian Park Hospital

Tualatin, Oregon, 97062, United States
Legacy Mount Hood Medical Center

Gresham, Oregon, 97030, United States
Liberty Hospital

Liberty, Missouri, 64068, United States
Licking Memorial Hospital

Newark, Ohio, 43055, United States
Logan Health Medical Center

Kalispell, Montana, 59901, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
Margaret R Pardee Memorial Hospital

Hendersonville, North Carolina, 28791, United States
Marietta Memorial Hospital

Marietta, Ohio, 45750, United States
Mary Rutan Hospital

Bellefontaine, Ohio, 43311, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Menorah Medical Center

Overland Park, Kansas, 66209, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Infusion Center - Chippewa

St Louis, Missouri, 63109, United States
Miami Valley Hospital

Dayton, Ohio, 45409, United States
Miami Valley Hospital North

Dayton, Ohio, 45415, United States
Michigan Cancer Research Consortium NCORP

Ann Arbor, Michigan, 48106, United States
Minor and James Medical PLLC

Seattle, Washington, 98104, United States
Montana Cancer Consortium NCORP

Billings, Montana, 59102, United States
Montana Cancer Specialists

Missoula, Montana, 59802, United States
Mount Carmel Health Center West

Columbus, Ohio, 43222, United States
Munson Medical Center

Traverse City, Michigan, 49684, United States
MyMichigan Medical Center Saginaw

Saginaw, Michigan, 48601, United States
North Kansas City Hospital

Kansas City, Missouri, 64116, United States
Northern Montana Hospital

Havre, Montana, 59501, United States
Northern Rockies Radiation Oncology Center

Billings, Montana, 59101, United States
Novant Health Presbyterian Medical Center

Charlotte, North Carolina, 28204, United States
OSF Saint Anthony's Health Center

Alton, Illinois, 62002, United States
PeaceHealth Saint Joseph Medical Center

Bellingham, Washington, 98225, United States
PeaceHealth Southwest Medical Center

Vancouver, Washington, 98664, United States
PeaceHealth United General Medical Center

Sedro-Woolley, Washington, 98284, United States
Providence Milwaukie Hospital

Milwaukie, Oregon, 97222, United States
Providence Newberg Medical Center

Newberg, Oregon, 97132, United States
Providence Portland Medical Center

Portland, Oregon, 97213, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center

Burbank, California, 91505, United States
Providence Saint Vincent Medical Center

Portland, Oregon, 97225, United States
Providence Willamette Falls Medical Center

Oregon City, Oregon, 97045, United States
Reid Health

Richmond, Indiana, 47374, United States
Research Medical Center

Kansas City, Missouri, 64132, United States
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Rocky Mountain Oncology

Casper, Wyoming, 82609, United States
Rutherford Hospital

Rutherfordton, North Carolina, 28139, United States
SSM Health Good Samaritan

Mount Vernon, Illinois, 62864, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Ann's Hospital

Westerville, Ohio, 43081, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint Joseph Health Center

Kansas City, Missouri, 64114, United States
Saint Louis-Cape Girardeau CCOP

St Louis, Missouri, 63141, United States
Saint Luke's East - Lee's Summit

Lee's Summit, Missouri, 64086, United States
Saint Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States
Saint Luke's South Hospital

Overland Park, Kansas, 66213, United States
Saint Michael Cancer Center

Silverdale, Washington, 98383, United States
Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802, United States
Saint Peter's Community Hospital

Helena, Montana, 59601, United States
Saint Vincent Frontier Cancer Center

Billings, Montana, 59102, United States
Saint Vincent Healthcare

Billings, Montana, 59101, United States
Salem Hospital

Salem, Oregon, 97301, United States
Salina Regional Health Center

Salina, Kansas, 67401, United States
Skagit Valley Hospital

Mount Vernon, Washington, 98274, United States
Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105, United States
Southeast Clinical Oncology Research Consortium NCORP

Winston-Salem, North Carolina, 27104, United States
Southeast Missouri Hospital

Cape Girardeau, Missouri, 63701, United States
Southern Ohio Medical Center

Portsmouth, Ohio, 45662, United States
Southwest Medical Center

Liberal, Kansas, 67901, United States
Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States
Spectrum Health Big Rapids Hospital

Big Rapids, Michigan, 49307, United States
Springfield Memorial Hospital

Springfield, Illinois, 62781, United States
Springfield Regional Medical Center

Springfield, Ohio, 45504, United States
Stanford Cancer Institute Palo Alto

Palo Alto, California, 94304, United States
Swedish Cancer Institute-Issaquah

Issaquah, Washington, 98029, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122, United States
The Don and Sybil Harrington Cancer Center

Amarillo, Texas, 79106, United States
Trinity Health Grand Rapids Hospital

Grand Rapids, Michigan, 49503, United States
Trinity Health Muskegon Hospital

Muskegon, Michigan, 49444, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106, United States
Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, 48341, United States
Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154, United States
Tulane University School of Medicine

New Orleans, Louisiana, 70112, United States
University Health Truman Medical Center

Kansas City, Missouri, 64108, United States
University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of Kentucky/Markey Cancer Center

Lexington, Kentucky, 40536, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Rochester

Rochester, New York, 14642, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
Wayne Memorial Hospital

Goldsboro, North Carolina, 27534, United States
Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Welch Cancer Center

Sheridan, Wyoming, 82801, United States
Wenatchee Valley Hospital and Clinics

Wenatchee, Washington, 98801, United States
Wesley Medical Center

Wichita, Kansas, 67214, United States
Wichita NCI Community Oncology Research Program

Wichita, Kansas, 67214, United States

Conditions

Explore the condition pages connected to this study.