New drug combo aims to make leukemia transplants safer and more effective

NCT ID NCT07232953

Summary

This study is testing a specific combination of two drugs (fludarabine and treosulfan) given to patients before they receive a stem cell transplant for acute myeloid leukemia (AML). The goal is to see if this drug regimen helps control the leukemia better while causing fewer severe side effects than some standard treatments. The trial is for adults aged 40-65 whose leukemia is currently in remission.

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Contacts and locations

Locations

  • ASST degli Spedali Civili di Brescia

    Brescia, Lombardy, 25123, Italy

  • Azienda Ospedaliera S. Croce e Carle

    Cuneo, Piedmont, 12100, Italy

  • Azienda Ospedaliera Universitaria Integrata Verona

    Verona, Veneto, 37126, Italy

  • Azienda Ospedaliera Universitaria di Modena

    Modena, Emilia-Romagna, 41124, Italy

  • Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli

    Naples, Campania, 80131, Italy

  • Azienda Ospedaliero Universitaria Careggi

    Florence, Tuscany, 50134, Italy

  • Azienda Sanitaria Universitaria Friuli Centrale

    Udine, Friuli Venezia Giulia, 33100, Italy

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico,

    Milan, Lombardy, 20122, Italy

  • Grande Ospedale Metropolitano "Bianco Melacrino Morelli"

    Reggio Calabria, Calabria, 89124, Italy

  • IRCCS Ospedale San Raffaele

    Milan, Lombardy, 20132, Italy

  • Ospedale C e G Mazzoni

    Ascoli Piceno, The Marches, 63100, Italy

  • Ospedale dell'Angelo

    Mestre, Veneto, 30174, Italy

  • Ospedali Riuniti di Ancona

    Ancona, The Marches, 60126, Italy

Conditions

Explore the condition pages connected to this study.