Scientists test new combo against tough blood cancers
NCT ID NCT03772925
Summary
This early-stage study tested a combination of two chemotherapy drugs, pevonedistat and belinostat, in adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that had returned or stopped responding to other treatments. The main goal was to find the highest dose of the drug pair that patients could tolerate without severe side effects. Researchers also looked for any early signs that the treatment might help control the cancer.
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Contacts and locations
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Locations
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Moffitt Cancer Center - McKinley Campus
Tampa, Florida, 33612, United States
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Moffitt Cancer Center-International Plaza
Tampa, Florida, 33607, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
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UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390, United States
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Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, 23298, United States
Conditions
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