New strategy aims to make leukemia cells more vulnerable to chemo
NCT ID NCT01627041
Summary
This study is testing whether adding a drug called decitabine before standard chemotherapy helps treat acute myeloid leukemia (AML) more effectively. The goal is to see if decitabine can 'prime' or sensitize the cancer cells, making them easier for the chemotherapy drugs to kill. The trial enrolled 178 adults with AML to compare the standard chemo alone against the new two-step approach. Researchers are measuring if this leads to more patients achieving remission.
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Contacts and locations
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Locations
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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Lafayette Family Cancer Center-EMMC
Brewer, Maine, 04412, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467, United States
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Montefiore Medical Center-Weiler Hospital
The Bronx, New York, 10461, United States
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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032, United States
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NYP/Weill Cornell Medical Center
New York, New York, 10065, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
Conditions
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