New chemo combo shows promise in AML consolidation trial

NCT ID NCT00932412

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 34 times

Summary

This study tested two different chemotherapy combinations as follow-up treatment (consolidation) in younger adults (ages 18-59) with newly diagnosed acute myeloid leukemia (AML) who achieved remission after initial therapy. The goal was to see which regimen better prevents the cancer from returning. Participants received either the experimental CLARA regimen or the standard high-dose cytarabine (HDAC) regimen. The study measured how long patients remained cancer-free and monitored side effects.

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Contacts and locations

Locations

  • CHU - Hôtel Dieu

    Nantes, 44093, France

  • CHU Dupuytren

    Limoges, 87042, France

  • CHU de Brabois

    Vandœuvre-lès-Nancy, 54511, France

  • Centre A. Lacassagne

    Nice, 06100, France

  • Centre Henri Becquerel - CHRU ROUEN

    Rouen, 76038, France

  • Centre Hospitalier Boulogne/Mer

    Boulogne / Mer, 62280, France

  • Centre Hospitalier Dunkerque

    Dunkirk, 59395, France

  • Centre Hospitalier Huguenin

    Saint-Cloud, 92210, France

  • Centre Hospitalier Meaux

    Meaux, 77104, France

  • Centre Hospitalier Regional et Universitaire d'Angers

    Angers, 49033, France

  • Centre Hospitalier René Dubos

    Cergy-Pontoise, 95303, France

  • Centre Hospitalier Schaffner

    Lens, 62307, France

  • Centre Hospitalier Valenciennes

    Valenciennes, 59322, France

  • Centre Hospitalier Versailles

    Le Chesnay, 78150, France

  • HIA Percy

    Clamart, 92141, France

  • Hospices Civils de Lyon - Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Hôpital Archet 1

    Nice, 06202, France

  • Hôpital Avicenne - bobigny

    Bobigny, 93009, France

  • Hôpital Clemenceau - chu Caen

    Caen, 14033, France

  • Hôpital Dubocage

    Dijon, 21000, France

  • Hôpital Haut Lévêque

    Pessac, 33604, France

  • Hôpital Huriez

    Lille, 59037, France

  • Hôpital Michallon

    Grenoble, 38043, France

  • Hôpital Mondor

    Créteil, 94010, France

  • Hôpital Purpan

    Toulouse, 31059, France

  • Hôpital St Louis

    Paris, 75010, France

  • Hôpital Sud - CHU Amiens

    Amiens, 80054, France

  • Hôpital V. Provo

    Roubaix, 59056, France

  • Hôpital Victor Dupouy

    Argenteuil, 95107, France

  • Hôpital de Corbeil

    Corbeil, 91100, France

  • Institut Gustave Roussy

    Villejuif, 94800, France

  • Institut Paoli-Calmette

    Marseille, 13273, France

  • Paris Necker

    Paris, 75743, France

  • Pitié-Salpetrière

    Paris, 75013, France

Conditions

Explore the condition pages connected to this study.