New drug duo targets tough lung cancer mutation
NCT ID NCT07227025
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 3 times
Summary
This study tests a combination of two drugs, amivantamab and olomorasib, in people with a specific type of advanced lung cancer (KRAS G12C mutant NSCLC) that has spread. The goal is to find the safest and most effective dose and see if the combo can shrink tumors or slow their growth. About 60 participants will be enrolled, and the study is currently recruiting.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CARCINOMA, NON-SMALL-CELL LUNG are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ankara Bilkent Sehir Hastanesi
RECRUITINGÇankaya, 06800, Turkey (Türkiye)
-
Ankara Universitesi Hastaneleri Tibbi Farmakoloji Anabilim Dali Faz 1 Klinik Arastirma Merkezi
RECRUITINGAnkara, 06620, Turkey (Türkiye)
-
Asan Medical Center
RECRUITINGSeoul, 05505, South Korea
-
Harbin medical university cancer hospital
RECRUITINGHarbin, 150000, China
-
Koc Universitesi Hastanesi Faz 1 Klinik Arastirma Merkezi
RECRUITINGIstanbul, 34010, Turkey (Türkiye)
-
New York University Langone Medical Center
RECRUITINGNew York, New York, 10016, United States
-
Oncology Consultants Cancer Center
SUSPENDEDHouston, Texas, 77030, United States
-
Princess Margaret Hospital
RECRUITINGToronto, Ontario, M5G 2M9, Canada
-
Samsung Medical Center
RECRUITINGSeoul, 06351, South Korea
-
Severance Hospital Yonsei University Health System
RECRUITINGSeoul, 03722, South Korea
-
Shanghai East Hospital
RECRUITINGShanghai, 310000, China
-
The First Affiliated Hospital Sun Yat sen University
RECRUITINGGuangzhou, 510060, China
-
Virginia Cancer Specialists
RECRUITINGFairfax, Virginia, 22031, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can immunotherapy be safely used in early lung cancer? a Real-World study investigates
- Can an oral chemo pill boost immunotherapy's power against lung cancer?
- Can an immunotherapy cocktail shrink inoperable lung tumors?
- Immunotherapy boosts radiation against early lung cancer
- Lab-Grown lung tumors could reveal why some drugs work and others fail
- AI-Powered navigation aims to pinpoint tiny lung nodules during surgery