Experimental myeloma drug trial halted early: what we know

NCT ID NCT03287908

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 21 times

Summary

This study tested an experimental drug called AMG 701, alone or with other medicines, in 174 adults with multiple myeloma that had come back or stopped responding to prior treatments. The main goals were to check safety and find the best dose. The trial was stopped early, so results are limited.

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Contacts and locations

Locations

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Gunma University Hospital

    Maebashi, Gunma, 371-8511, Japan

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Icahn School of Medicine at Mount Sinai

    Hackensack, New Jersey, 07601, United States

  • Kanazawa University Hospital

    Kanazawa, Ishikawa-ken, 920-8641, Japan

  • Kobe City Medical Center General Hospital

    Kobe, Hyōgo, 650-0047, Japan

  • Levine Cancer Institute

    Charlotte, North Carolina, 28204, United States

  • Maastricht Universitair Medisch Centrum

    Maastricht, 6229 HX, Netherlands

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic - Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • McGill University Health Centre Glen Site

    Montreal, Quebec, H4A 3J1, Canada

  • Nagoya City University Hospital

    Nagoya, Aichi-ken, 467-8602, Japan

  • National Hospital Organization Okayama Medical Center

    Okayama, Okayama-ken, 701-1192, Japan

  • New York Presbyterian Hospital, Weill Cornell Medical College

    New York, New York, 10065, United States

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

  • The Alfred Hospital

    Melbourne, Victoria, 3004, Australia

  • The Cancer Institute Hospital of Japanese Foundation for Cancer Research

    Koto-ku, Tokyo, 135-8550, Japan

  • The Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Universitaetsklinikum Wuerzburg

    Würzburg, 97080, Germany

  • Universitair Medisch Centrum Groningen

    Groningen, 9713 GZ, Netherlands

  • Universitair Medisch Centrum Utrecht

    Utrecht, 3584 CX, Netherlands

  • University Health Network-Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 1X6, Canada

  • University of Arkansas for Medical Sciences Myeloma Institute Slot 816

    Little Rock, Arkansas, 72205, United States

  • University of Chicago Medical Center - Multiple Myeloma Research Consortium

    Chicago, Illinois, 60637, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of Utah Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

  • Universitätsklinikum Heidelberg

    Heidelberg, 69120, Germany

  • Universitätsklinikum Schleswig Holstein Campus Kiel

    Kiel, 24105, Germany

  • Wake Forest Baptist Health

    Winston-Salem, North Carolina, 27157, United States

  • Washington University

    St Louis, Missouri, 63110, United States

  • Winship Cancer Institute Emory U

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.