First look: new pill targets 'Undruggable' cancer mutation in chinese patients

NCT ID NCT04380753

Summary

This early-stage study tested a new oral drug called AMG 510 (sotorasib) in 12 patients of Chinese descent with advanced cancers that had a specific genetic change called KRAS G12C. The main goals were to check the drug's safety, how the body processes it, and see if it showed any early signs of shrinking tumors. This was a foundational study to gather initial data in this specific patient population.

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Contacts and locations

Locations

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Prince of Wales Hospital

    Shatin, New Territories, Hong Kong

  • University of Hong Kong, Queen Mary Hospital

    Hong Kong, Hong Kong

  • Veterans General Hospital - Taichung

    Taichung, 40705, Taiwan

Conditions

Explore the condition pages connected to this study.