New cancer drug enters first human trials

NCT ID NCT06131398

Summary

This is the first study in people testing a new drug called AMG 355, both by itself and combined with an existing immunotherapy (pembrolizumab). It aims to find safe doses and see if the treatment helps adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to check for side effects and determine the best dose for future studies.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alliance for Multispecialty Research - Kansas City

    Merriam, Kansas, 66204, United States

  • Asan Medical Center

    Seoul, 138-736, South Korea

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Erasmus Medisch Centrum

    Rotterdam, 3015 CE, Netherlands

  • Gustave Roussy

    Villejuif, 94805, France

  • Hospital Clinic i Provincial de Barcelona

    Barcelona, Catalonia, 08036, Spain

  • Hospital Universitari Vall d Hebron

    Barcelona, Catalonia, 08023, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, 28034, Spain

  • Institut Bergonie

    Bordeaux, 33076, France

  • Istituto Oncologico della Svizzera Italiana

    Bellinzona, 6500, Switzerland

  • Kantonsspital Sankt Gallen

    Sankt Gallen, 9007, Switzerland

  • Narodowy Instytut Onkologii im Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy

    Warsaw, 02-781, Poland

  • National Cancer Center Hospital East

    Kashiwa-shi, Chiba, 277-8577, Japan

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 1Z5, Canada

  • Radboud Universitair Medisch Centrum

    Nijmegen, 6525 GA, Netherlands

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • South Texas Accelerated Research Therapeutics

    San Antonio, Texas, 78229, United States

  • St Vincents Hospital Sydney

    Darlinghurst, New South Wales, 2010, Australia

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

  • The Cancer Institute Hospital of Japanese Foundation for Cancer Research

    Koto-ku, Tokyo, 135-8550, Japan

  • The Queen Elizabeth Hospital

    Woodville South, South Australia, 5011, Australia

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.