First patients test new cancer drug in early safety trial

NCT ID NCT05800964

Summary

This was the first study in humans to test a new cancer drug called AMG 305. It aimed to find a safe dose and see how the body processes the drug in 37 adults with advanced solid tumors who had run out of standard treatment options. The main goal was to check for side effects and determine the best dose for future studies.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Beatson West of Scotland Cancer Centre

    Glasgow, G12 0YN, United Kingdom

  • Chris OBrien Lifehouse

    Camperdown, New South Wales, 2050, Australia

  • Christie Hospital

    Manchester, M20 4BX, United Kingdom

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Freeman Hospital

    Newcastle, NE7 7DN, United Kingdom

  • Gustave Roussy

    Villejuif, 94805, France

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Hospital Clinic i Provincial de Barcelona

    Barcelona, Catalonia, 08036, Spain

  • Hospital Universitari Vall d Hebron

    Barcelona, Catalonia, 08035, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Madrid Sanchinarro

    Madrid, 28050, Spain

  • Institut Universitaire du Cancer Toulouse Oncopole

    Toulouse, 31059, France

  • National Cancer Center Hospital East

    Kashiwa-shi, Chiba, 277-8577, Japan

  • New York University Cancer Institute

    New York, New York, 10016, United States

  • Next Oncology

    San Antonio, Texas, 78229, United States

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2C1, Canada

  • Royal Marsden Hospital

    Sutton, SM2 5PT, United Kingdom

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute UK

    London, W1G 6AD, United Kingdom

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • Universitaetsklinikum Dresden

    Dresden, 01307, Germany

  • Universitaetsklinikum Essen

    Essen, 45147, Germany

  • Universitaetsklinikum Wuerzburg

    Würzburg, 97078, Germany

  • University College London Hospital

    London, W1T 7HA, United Kingdom

Conditions

Explore the condition pages connected to this study.